Detalhe da pesquisa
1.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Mol Cell
; 81(10): 2183-2200.e13, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019788
2.
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
; 126(21): 2392-403, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26447190
3.
Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms.
J Immunol
; 185(1): 367-75, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20530266
4.
BET Inhibition Enhances TNF-Mediated Antitumor Immunity.
Cancer Immunol Res
; 10(1): 87-107, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34782346
5.
Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML.
Cancer Discov
; 12(6): 1560-1579, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35311997
6.
Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors.
Blood
; 113(9): 1982-91, 2009 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19060243
7.
The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.
Blood
; 114(2): 380-93, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19383971
8.
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity.
Sci Adv
; 6(18)2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917631
9.
Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin.
Mol Cancer Ther
; 7(5): 1066-79, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18483296
10.
A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens.
Methods Mol Biol
; 1725: 201-227, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29322420
11.
BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.
Cell Rep
; 18(9): 2162-2174, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28249162
12.
BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members.
Mol Cancer Ther
; 15(9): 2030-41, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27406984
13.
An intact immune system is required for the anticancer activities of histone deacetylase inhibitors.
Cancer Res
; 73(24): 7265-76, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24158093
14.
Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities.
Mol Cancer Ther
; 12(12): 2709-21, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24092806
15.
Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.
Cancer Res
; 71(10): 3603-15, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21398407
16.
Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses.
Immunol Cell Biol
; 80(3): 231-40, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12067410
17.
The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes.
J Immunol
; 168(7): 3376-86, 2002 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11907095
18.
SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis.
Immunity
; 20(2): 153-65, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14975238