Detalhe da pesquisa
1.
Activation of the GLP-1 receptor by a non-peptidic agonist.
Nature
; 577(7790): 432-436, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915381
2.
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature
; 555(7694): 121-125, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29466332
3.
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism.
J Biol Chem
; 293(24): 9370-9387, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29717000
4.
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun
; 13(1): 92, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013280
5.
Glucagon-like peptide-1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists.
Biochem Pharmacol
; 156: 406-419, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30195733
6.
Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1.
Biochem Pharmacol
; 136: 99-108, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28363772