Detalhe da pesquisa
1.
Clinical Presentation of Connective Tissue Disease Patients with and without Interstitial Lung Disease: A Retrospective Study.
Respiration
; 102(6): 405-415, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37231870
2.
Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives.
Molecules
; 28(7)2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37049935
3.
Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Proc Natl Acad Sci U S A
; 114(33): E6942-E6951, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760974
4.
An Enzymatic Flow-Based Preparative Route to Vidarabine.
Molecules
; 25(5)2020 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182773
5.
Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs.
Br J Cancer
; 120(5): 537-546, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30739913
6.
Synthesis and pharmacological evaluation of conformationally constrained glutamic acid higher homologues.
Bioorg Med Chem
; 24(22): 5741-5747, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27658797
7.
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases.
Bioorg Med Chem
; 24(12): 2654-9, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27137361
8.
Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase.
J Enzyme Inhib Med Chem
; 31(2): 295-301, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-25807299
9.
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation.
Bioorg Med Chem
; 23(21): 7053-60, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26432608
10.
Efficient synthesis of novel glutamate homologues and investigation of their affinity and selectivity profile at ionotropic glutamate receptors.
Bioorg Med Chem Lett
; 24(8): 1980-2, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630559
11.
Unveiling the Relationship between Ceftobiprole and High-Molecular-Mass (HMM) Penicillin-Binding Proteins (PBPs) in Enterococcus faecalis.
Antibiotics (Basel)
; 13(1)2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38247624
12.
An Aminoglycoside-Sparing Regimen with Double Beta-Lactam to Successfully Treat Granulicatella adiacens Prosthetic Aortic Valve Endocarditis-Time to Change Paradigm?
Infect Dis Rep
; 16(2): 249-259, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38525767
13.
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents.
ACS Infect Dis
; 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38717116
14.
Effect of glycosylation on the affinity of the MTB protein Ag85B for specific antibodies: towards the design of a dual-acting vaccine against tuberculosis.
Biol Direct
; 19(1): 11, 2024 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38268026
15.
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells.
Eur J Med Chem
; 254: 115286, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37058971
16.
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death.
J Biol Chem
; 286(16): 14007-18, 2011 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21335552
17.
Enzymatic continuous-flow preparation of nature-inspired phenolic esters as antiradical and antimicrobial agents.
Food Chem
; 390: 133195, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594770
18.
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death.
Cancers (Basel)
; 14(13)2022 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35804925
19.
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds.
ACS Med Chem Lett
; 12(11): 1726-1732, 2021 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34795860
20.
Synthesis of 3-aryl/benzyl-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole derivatives: a comparison between conventional, microwave-assisted and flow-based methodologies.
J Org Chem
; 75(21): 7439-42, 2010 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20882999