Detalhe da pesquisa
1.
Antinociceptive effects of α2/α3-subtype selective GABAA receptor positive allosteric modulators KRM-II-81 and NS16085 in rats: behavioral specificity.
J Pharmacol Exp Ther
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670800
2.
Transmission mode predicts coinfection patterns of insect-specific viruses in field populations of the Queensland fruit fly.
Mol Ecol
; 33(3): e17226, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38018898
3.
Vascular effects of midazolam, flumazenil, and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta.
Can J Physiol Pharmacol
; 102(3): 206-217, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37909404
4.
Development and validation of an LC-MS/MS method for the determination of ARN14988, an acid ceramidase inhibitor, and its application to a pharmacokinetic study in a mouse model.
Biomed Chromatogr
; 38(1): e5754, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37750452
5.
Bee pollination services and the burden of biogeography.
Proc Biol Sci
; 290(2000): 20230747, 2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37312542
6.
Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation.
J Pharmacol Exp Ther
; 385(1): 50-61, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746611
7.
Microbial diversity in stingless bee gut is linked to host wing size and influenced by the environment.
J Invertebr Pathol
; 198: 107909, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889457
8.
Heat stress survival and thermal tolerance of Australian stingless bees.
J Therm Biol
; 117: 103671, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37677867
9.
Comparative anticonvulsant activity of the GABAkine KRM-II-81 and a deuterated analog.
Drug Dev Res
; 84(3): 527-531, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36748904
10.
GL-II-73, a Positive Allosteric Modulator of α5GABAA Receptors, Reverses Dopamine System Dysfunction Associated with Pilocarpine-Induced Temporal Lobe Epilepsy.
Int J Mol Sci
; 24(14)2023 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37511346
11.
α5-GABAA Receptor Modulation Reverses Behavioral and Neurophysiological Correlates of Psychosis in Rats with Ventral Hippocampal Alzheimer's Disease-like Pathology.
Int J Mol Sci
; 24(14)2023 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37511546
12.
Synthesis and Receptor Binding Studies of α5 GABAAR Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders.
Molecules
; 28(12)2023 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37375326
13.
Common endosymbionts affect host fitness and sex allocation via egg size provisioning.
Proc Biol Sci
; 289(1971): 20212582, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35350856
14.
Pathogen to commensal? Longitudinal within-host population dynamics, evolution, and adaptation during a chronic >16-year Burkholderia pseudomallei infection.
PLoS Pathog
; 16(3): e1008298, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32134991
15.
Positive Allosteric Modulation of α5-GABAA Receptors Reverses Stress-Induced Alterations in Dopamine System Function and Prepulse Inhibition of Startle.
Int J Neuropsychopharmacol
; 25(8): 688-698, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732272
16.
Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies.
Bioorg Med Chem Lett
; 62: 128637, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35218882
17.
Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation.
Cereb Cortex
; 31(2): 1395-1408, 2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33068001
18.
Metabolism, pharmacokinetics, and anticonvulsant activity of a deuterated analog of the α2/3-selective GABAkine KRM-II-81.
Biopharm Drug Dispos
; 43(2): 66-75, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194800
19.
Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer.
Drug Dev Res
; 83(4): 979-992, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35246861
20.
Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor N4-Methyltalpinine.
Molecules
; 27(5)2022 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35268836