Detalhe da pesquisa
1.
Evaluation of both exonic and intronic variants for effects on RNA splicing allows for accurate assessment of the effectiveness of precision therapies.
PLoS Genet
; 16(10): e1009100, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085659
2.
Capitalizing on the heterogeneous effects of CFTR nonsense and frameshift variants to inform therapeutic strategy for cystic fibrosis.
PLoS Genet
; 14(11): e1007723, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30444886
3.
Synergy between Readthrough and Nonsense Mediated Decay Inhibition in a Murine Model of Cystic Fibrosis Nonsense Mutations.
Int J Mol Sci
; 22(1)2020 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33396210
4.
Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells.
Am J Physiol Lung Cell Mol Physiol
; 316(6): L1081-L1093, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30892081
5.
Linaclotide improves gastrointestinal transit in cystic fibrosis mice by inhibiting sodium/hydrogen exchanger 3.
Am J Physiol Gastrointest Liver Physiol
; 315(5): G868-G878, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30118317
6.
Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells.
Am J Physiol Lung Cell Mol Physiol
; 311(2): L317-27, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27317686
7.
Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells.
Traffic
; 14(3): 337-54, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23205726
8.
Role of Exchange Protein Activated by cAMP 1 in Regulating Rates of Microtubule Formation in Cystic Fibrosis Epithelial Cells.
Am J Respir Cell Mol Biol
; 53(6): 853-62, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25955407
9.
CX3CR1 is an important surface molecule for respiratory syncytial virus infection in human airway epithelial cells.
J Gen Virol
; 96(9): 2543-2556, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26297201
10.
Early developmental phenotypes in the cystic fibrosis sheep model.
FASEB Bioadv
; 5(1): 13-26, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36643895
11.
A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function.
Thorax
; 67(5): 385-91, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22169360
12.
Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus.
Proc Natl Acad Sci U S A
; 106(47): 19934-9, 2009 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19897727
13.
Cystic fibrosis growth retardation is not correlated with loss of Cftr in the intestinal epithelium.
Am J Physiol Gastrointest Liver Physiol
; 301(3): G528-36, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21659619
14.
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks.
J Cyst Fibros
; 19(1): 34-39, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31126900
15.
Electrochemical measurement of membrane cholesterol correlates with CFTR function and is HDAC6-dependent.
J Cyst Fibros
; 18(2): 175-181, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941319
16.
A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice.
Sci Rep
; 9(1): 11828, 2019 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413336
17.
CFTR modulator theratyping: Current status, gaps and future directions.
J Cyst Fibros
; 18(1): 22-34, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29934203
18.
Generation of a conditional null allele for Cftr in mice.
Genesis
; 46(10): 546-52, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18802965
19.
Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site.
J Gen Physiol
; 130(3): 313-28, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17724164
20.
Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells.
J Cyst Fibros
; 17(4): 444-453, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29459038