Detalhe da pesquisa
1.
Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR.
Int J Mol Sci
; 24(21)2023 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958944
2.
A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity.
Int J Mol Sci
; 23(17)2022 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36077163
3.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
Int J Mol Sci
; 22(18)2021 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34576014
4.
MAbTope: A Method for Improved Epitope Mapping.
J Immunol
; 201(10): 3096-3105, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322966
5.
FSH for the Treatment of Male Infertility.
Int J Mol Sci
; 21(7)2020 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32218314
6.
G protein-dependent signaling triggers a ß-arrestin-scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation.
FASEB J
; 32(3): 1154-1169, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084767
7.
Novel Role for p110ß PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.
PLoS Genet
; 11(7): e1005304, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132308
8.
The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway.
Development
; 141(10): 2096-107, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24803656
9.
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis.
Mol Cell Endocrinol
; 589: 112235, 2024 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621656
10.
A single-domain intrabody targeting the follicle-stimulating hormone receptor impacts FSH-induced G protein-dependent signalling.
FEBS Lett
; 598(2): 220-232, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37923554
11.
Competing G protein-coupled receptor kinases balance G protein and ß-arrestin signaling.
Mol Syst Biol
; 8: 590, 2012 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22735336
12.
Towards the convergent therapeutic potential of G protein-coupled receptors in autism spectrum disorders.
Br J Pharmacol
; 2023 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37574491
13.
Intracellular VHHs to monitor and modulate GPCR signaling.
Front Endocrinol (Lausanne)
; 13: 1048601, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36465650
14.
Novel pathways in gonadotropin receptor signaling and biased agonism.
Rev Endocr Metab Disord
; 12(4): 259-74, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21526415
15.
Accurate determination of epitope for antibodies with unknown 3D structures.
MAbs
; 13(1): 1961349, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34432559
16.
Direct impact of gonadotropins on glucose uptake and storage in preovulatory granulosa cells: Implications in the pathogenesis of polycystic ovary syndrome.
Metabolism
; 115: 154458, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33278413
17.
Methionine deprivation regulates the S6K1 pathway and protein synthesis in avian QM7 myoblasts without activating the GCN2/eIF2 alpha cascade.
J Nutr
; 140(9): 1539-45, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20610638
18.
Developmental regulation of p70 S6 kinase by a G protein-coupled receptor dynamically modelized in primary cells.
Cell Mol Life Sci
; 66(21): 3487-503, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19730801
19.
Mathematical modeling approaches of cellular endocrinology within the hypothalamo-pituitary-gonadal axis.
Mol Cell Endocrinol
; 518: 110877, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32569857
20.
Follicle-stimulating Hormone (FSH) Action on Spermatogenesis: A Focus on Physiological and Therapeutic Roles.
J Clin Med
; 9(4)2020 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32260182