Detalhe da pesquisa
1.
Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.
Gene Ther
; 2023 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37587230
2.
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human ß-globin locus.
Blood
; 131(17): 1960-1973, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29519807
3.
Correction: Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.
Gene Ther
; 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38212405
4.
The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.
Mol Ther
; 24(3): 645-54, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26782639
5.
Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing.
Mol Ther
; 24(3): 475-87, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26750397
6.
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.
Mol Ther
; 24(3): 636-44, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26658966
7.
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection.
Proc Natl Acad Sci U S A
; 111(26): 9591-6, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24927590
8.
An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.
Nucleic Acids Res
; 42(6): e42, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24381193
9.
TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity.
Nucleic Acids Res
; 42(10): 6762-73, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24792154
10.
CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.
Nucleic Acids Res
; 42(11): 7473-85, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24838573
11.
SAPTA: a new design tool for improving TALE nuclease activity.
Nucleic Acids Res
; 42(6): e47, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442582
12.
CRISPR/Cas9 systems targeting ß-globin and CCR5 genes have substantial off-target activity.
Nucleic Acids Res
; 41(20): 9584-92, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23939622
13.
Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.
Nucleic Acids Res
; 40(12): 5560-8, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22373919
14.
Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells.
Mol Ther Nucleic Acids
; 32: 1010-1025, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37346975
15.
ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites.
BMC Bioinformatics
; 12: 152, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21569489
16.
Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs.
Mol Ther
; 18(5): 947-54, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20160705
17.
In vivo genome editing at the albumin locus to treat methylmalonic acidemia.
Mol Ther Methods Clin Dev
; 23: 619-632, 2021 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34901307
18.
Base Editors Flex Sights on Sickle-Cell Disease.
CRISPR J
; 4(2): 166-168, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876950
19.
TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs.
Mol Ther Nucleic Acids
; 5: e273, 2016 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26730810
20.
Designing and testing the activities of TAL effector nucleases.
Methods Mol Biol
; 1114: 203-19, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24557905