Detalhe da pesquisa
1.
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing.
Biotechnol Bioeng
; 121(4): 1284-1297, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240126
2.
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing.
Biotechnol Bioeng
; 121(1): 291-305, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37877536
3.
Evaluation of preferred binding regions on ubiquitin and IgG1 FC for interacting with multimodal cation exchange resins using DEPC labeling/mass spectrometry.
Biotechnol Bioeng
; 120(6): 1592-1604, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36814367
4.
Implications of AAV affinity column reuse and vector stability on product quality attributes.
Biotechnol Bioeng
; 2023 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37485847
5.
Continuous precipitation-filtration process for initial capture of a monoclonal antibody product using a four-stage countercurrent hollow fiber membrane washing step.
Biotechnol Bioeng
; 2023 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37565527
6.
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing.
Biotechnol Bioeng
; 120(4): 1068-1080, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585356
7.
Association of Frailty, Age, and Biological Sex With Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine-Induced Immunity in Older Adults.
Clin Infect Dis
; 75(Suppl 1): S61-S71, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35607747
8.
Systematic workflow for studying domain contributions of bispecific antibodies to selectivity in multimodal chromatography.
Biotechnol Bioeng
; 119(1): 211-225, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34687215
9.
Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents.
Biotechnol Bioeng
; 119(7): 1873-1889, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377460
10.
Rapid optimization of processes for the integrated purification of biopharmaceuticals.
Biotechnol Bioeng
; 118(9): 3435-3446, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782945
11.
Identification of preferred multimodal ligand-binding regions on IgG1 FC using nuclear magnetic resonance and molecular dynamics simulations.
Biotechnol Bioeng
; 118(2): 809-822, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33107976
12.
Development of a platform process for the production and purification of single-domain antibodies.
Biotechnol Bioeng
; 118(9): 3348-3358, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33624832
13.
Probing IgG1 FC-Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach.
Langmuir
; 37(41): 12188-12203, 2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34633195
14.
Mechanism of sequence-based separation of single-stranded DNA in capillary zone electrophoresis.
Electrophoresis
; 41(9): 705-713, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32031267
15.
The Role of Ligand-Ligand Interactions in Multimodal Ligand Conformational Equilibria and Surface Pattern Formation.
Langmuir
; 36(31): 9054-9063, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589849
16.
Investigation of cathepsin D-mAb interactions using a combined experimental and computational tool set.
Biotechnol Bioeng
; 116(7): 1684-1697, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30882893
17.
A combined screening and in silico strategy for the rapid design of integrated downstream processes for process and product-related impurity removal.
Biotechnol Bioeng
; 116(9): 2178-2190, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31081177
18.
Formation of Ligand Clusters on Multimodal Chromatographic Surfaces.
Langmuir
; 35(51): 16770-16779, 2019 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31603330
19.
Protein Binding Kinetics in Multimodal Systems: Implications for Protein Separations.
Anal Chem
; 90(4): 2609-2617, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29212318
20.
An impurity characterization based approach for the rapid development of integrated downstream purification processes.
Biotechnol Bioeng
; 115(8): 2048-2060, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29679482