Detalhe da pesquisa
1.
Functionalized 1,2,3-triazolium salts as potential agents against visceral leishmaniasis.
Parasitol Res
; 121(5): 1389-1406, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169883
2.
Oral pentamidine-loaded poly(d,l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment.
Nanotechnology
; 30(45): 455102, 2019 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31365912
3.
Preclinical Studies Evaluating Subacute Toxicity and Therapeutic Efficacy of LQB-118 in Experimental Visceral Leishmaniasis.
Antimicrob Agents Chemother
; 60(6): 3794-801, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27067332
4.
Antileishmanial Activity of Ezetimibe: Inhibition of Sterol Biosynthesis, In Vitro Synergy with Azoles, and Efficacy in Experimental Cutaneous Leishmaniasis.
Antimicrob Agents Chemother
; 60(11): 6844-6852, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27600041
5.
The new pyrazolyltetrazole derivative MSN20 is effective via oral delivery against cutaneous leishmaniasis.
Antimicrob Agents Chemother
; 58(10): 6290-3, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092697
6.
LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis.
J Antimicrob Chemother
; 68(4): 789-99, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23288404
7.
Biological effects of trans, trans-farnesol in Leishmania amazonensis.
Front Cell Infect Microbiol
; 13: 1221246, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38035328
8.
Effects of anti-Leishmania compounds in the behavior of the sand fly vector Lutzomyia longipalpis.
Pest Manag Sci
; 78(7): 2792-2805, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411662
9.
Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis.
J Antimicrob Chemother
; 66(7): 1555-9, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21531758
10.
Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis.
Bioorg Med Chem
; 19(22): 6885-91, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22000949
11.
Efficacy of Spironolactone Treatment in Murine Models of Cutaneous and Visceral Leishmaniasis.
Front Pharmacol
; 12: 636265, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33927619
12.
Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity.
ACS Med Chem Lett
; 12(9): 1405-1412, 2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34531949
13.
Editorial: Strategies in the drug discovery and development for leishmaniasis: immunomodulators, natural products, synthetic compounds, and drug repositioning.
Front Cell Infect Microbiol
; 14: 1384244, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38544526
14.
Leishmaniasis treatment: update of possibilities for drug repurposing.
Front Biosci (Landmark Ed)
; 23(5): 967-996, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28930585
15.
Second-generation pterocarpanquinones: synthesis and antileishmanial activity.
J Venom Anim Toxins Incl Trop Dis
; 24: 35, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30519257
16.
Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection.
Drug Des Devel Ther
; 11: 1095-1105, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28435221
17.
Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.
PLoS Negl Trop Dis
; 11(1): e0005281, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28045892
18.
Oral effectiveness of PMIC4, a novel hydroxyethylpiperazine analogue, in Leishmania amazonensis.
Int J Parasitol Drugs Drug Resist
; 4(3): 210-3, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25516829
19.
Second-generation pterocarpanquinones: synthesis and antileishmanial activity
J. venom. anim. toxins incl. trop. dis
; 24: 35, 2018. tab, graf, ilus
Artigo
em Inglês
| LILACS, VETINDEX | ID: biblio-976030
20.
The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis.
Acta Trop
; 119(2-3): 194-8, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21601554