Detalhe da pesquisa
1.
DARTpaths, an in silico platform to investigate molecular mechanisms of compounds.
Bioinformatics
; 39(1)2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36477801
2.
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity.
Arch Toxicol
; 97(8): 2291-2302, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296313
3.
A new paradigm for regulatory sciences.
Regul Toxicol Pharmacol
; 145: 105524, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37925098
4.
Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum.
Regul Toxicol Pharmacol
; 144: 105483, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640101
5.
A mathematical model of the role of aggregation in sonic hedgehog signalling.
PLoS Comput Biol
; 17(2): e1008562, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617524
6.
An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.
Xenobiotica
; 50(3): 318-322, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31180273
7.
Cardiovascular Effects and Molecular Mechanisms of Bisphenol A and Its Metabolite MBP in Zebrafish.
Environ Sci Technol
; 53(1): 463-474, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520632
8.
Developing prototypes of a modernized approach to assess crop protection chemical safety.
ALTEX
; 41(1): 119-130, 2024 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37658815
9.
New approach methodologies (NAMs): identifying and overcoming hurdles to accelerated adoption.
Toxicol Res (Camb)
; 13(2): tfae044, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38533179
10.
A metabolomics investigation of non-genotoxic carcinogenicity in the rat.
J Proteome Res
; 12(12): 5775-90, 2013 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161236
11.
Predictive liver lipid biomarker signature of Acetyl-coenzyme A carboxylase inhibitor related developmental toxicity in non-pregnant female Han Wistar rats - Lipidomics biomarker discovery and validation.
Toxicol Lett
; 380: 62-68, 2023 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996930
12.
Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration.
ALTEX
; 40(3): 534-540, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36888967
13.
Toxicogenomics: the challenges and opportunities to identify biomarkers, signatures and thresholds to support mode-of-action.
Mutat Res
; 746(2): 97-103, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22445948
14.
Transforming the evaluation of agrochemicals.
Pest Manag Sci
; 78(12): 5049-5056, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36317936
15.
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.
Toxicol Sci
; 190(2): 127-132, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165699
16.
Exploration of the DARTable Genome- a Resource Enabling Data-Driven NAMs for Developmental and Reproductive Toxicity Prediction.
Front Toxicol
; 3: 806311, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35295108
17.
An evaluation of carcinogenicity predictors from short-term and sub chronic repeat-dose studies of agrochemicals in rats: Opportunities to refine and reduce animal use.
Toxicol Lett
; 351: 18-27, 2021 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34364947
18.
Comparison of the predictive nature of the Genomic Allergen Rapid Detection (GARD) assay with mammalian assays in determining the skin sensitisation potential of agrochemical active ingredients.
Toxicol In Vitro
; 70: 105017, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33038465
19.
Species differences in phenobarbital-mediated UGT gene induction in rat and human liver microtissues.
Toxicol Rep
; 8: 155-161, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33473352
20.
An integrated functional genomic study of acute phenobarbital exposure in the rat.
BMC Genomics
; 11: 9, 2010 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20053287