Detalhe da pesquisa
1.
A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance.
PLoS Pathog
; 19(1): e1011081, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36701396
2.
Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica.
Mol Cell Proteomics
; 22(12): 100684, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993102
3.
Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins.
PLoS Pathog
; 18(1): e1010226, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007288
4.
Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica.
BMC Genomics
; 23(1): 419, 2022 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35659245
5.
Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system.
Epidemiol Infect
; 150: e128, 2022 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723031
6.
Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver.
BMC Genomics
; 22(1): 46, 2021 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33430759
7.
Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling.
BMC Genomics
; 22(1): 274, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33858339
8.
Antigen-specific response of CD4+ T cells and hepatic lymph node cells to Fasciola hepatica-derived molecules at the early and late stage of the infection in sheep.
Vet Res
; 52(1): 99, 2021 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34215335
9.
Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests.
Epidemiol Infect
; 149: e140, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099081
10.
Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host.
Mol Cell Proteomics
; 17(4): 792-809, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321187
11.
Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts.
BMC Genomics
; 20(1): 729, 2019 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31606027
12.
Fasciola hepatica Surface Tegument: Glycoproteins at the Interface of Parasite and Host.
Mol Cell Proteomics
; 15(10): 3139-3153, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466253
13.
Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES.
J Biol Chem
; 291(37): 19220-34, 2016 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27422822
14.
The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis.
Mol Cell Proteomics
; 14(12): 3258-73, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26486420
15.
Exploring the utility of circulating miRNAs as diagnostic biomarkers of fasciolosis.
Sci Rep
; 14(1): 7431, 2024 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38548871
16.
The use of cathepsin L1 (FhCL1) serological ELISA in sentinel screening for liver fluke on sheep farms.
Vet Parasitol Reg Stud Reports
; 45: 100924, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783527
17.
Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection.
Vet Parasitol
; 323: 110049, 2023 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37826973
18.
Omics tools enabling vaccine discovery against fasciolosis.
Trends Parasitol
; 38(12): 1068-1079, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36270885
19.
Exploiting Comparative Omics to Understand the Pathogenic and Virulence-Associated Protease: Anti-Protease Relationships in the Zoonotic Parasites Fasciola hepatica and Fasciola gigantica.
Genes (Basel)
; 13(10)2022 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36292739
20.
Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during Growth and Development.
Antioxidants (Basel)
; 11(10)2022 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36290692