Detalhe da pesquisa
1.
Fluorous-Phase Approach to α-Hydroxytropolone Synthesis.
J Org Chem
; 83(3): 1478-1485, 2018 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338231
2.
Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors.
Biochemistry
; 55(5): 809-19, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26829613
3.
Synthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses.
Antimicrob Agents Chemother
; 60(4): 2140-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26787704
4.
Discovery and Development of a Three-Component Oxidopyrylium [5 + 2] Cycloaddition.
J Org Chem
; 81(9): 3744-51, 2016 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27018974
5.
Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity.
Antimicrob Agents Chemother
; 59(2): 1070-9, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25451058
6.
Inhibition of the ANT(2")-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones.
Bioorg Med Chem Lett
; 24(21): 4943-7, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25283553
7.
7,9-Diaryl-1,6,8-trioxaspiro[4.5]dec-3-en-2-ones: readily accessible and highly potent anticancer compounds.
Bioorg Med Chem Lett
; 24(16): 4035-8, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25011911
8.
Discovery of 5'-Substituted 5-Fluoro-2'-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors.
ACS Pharmacol Transl Sci
; 6(5): 702-709, 2023 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37200809
9.
Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 Mpro Inhibitors.
ACS Med Chem Lett
; 14(10): 1434-1440, 2023 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37849558
10.
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.
ACS Chem Neurosci
; 14(17): 3059-3076, 2023 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37566734
11.
Free Energy-Based Virtual Screening and Optimization of RNase H Inhibitors of HIV-1 Reverse Transcriptase.
ACS Omega
; 1(3): 435-447, 2016 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27713931
12.
Traceless Solid-Phase α-Hydroxytropolone Synthesis.
Medchemcomm
; 7(9): 1789-1792, 2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28090282
13.
Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity.
Medchemcomm
; 7(9): 1783-1788, 2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28093576
14.
The biology and synthesis of α-hydroxytropolones.
Medchemcomm
; 5(7): 842-852, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25089179