Analysis of Customer Satisfaction relating to the vaccination campaign aimed at extremely vulnerable people in the Asl of Latina. / Analisi della Customer Satisfaction relativa la campagna vaccinale rivolta alle persone estremamente vulnerabili nella Asl di Latina.

INTRODUCTION: Customer Satisfaction is a tool for assessing the effectiveness and efficiency of the service offered and related corrective measures to improve the quality of services provided by hospitals Collection and analysis of data regarding customer satisfaction during the vaccination campaign was estremely important. METHOD: A specific analisys on extremely vulnerable people during the vaccination campaign. An observational study was conducted through a survey on a List of extremely vulnerable people provided by specialists to the Medical Management. RESULTS: There was good feedback with the return of most of the questionnaires administered and above all a good degree of satisfaction and protection on the part of the user. CONCLUSION: The analysis carried out found that by placing the centrality of the person, "patient-oriented" in the foreground, with listening, the "taken care of", creates an empathic relationship between the healthcare professional and the user. This humanization makes the user feel satisfied and above all protected even during such a particular path as vaccination.

Effectiveness, Tolerability and Prescribing Choice of Antiviral Molecules Molnupiravir, Remdesivir and Nirmatrelvir/r: A Real-World Comparison in the First Ten Months of Use.

In 2022, three antiviral drugs-molnupiravir, remdesivir and nirmatrelvir/ritonavir-were introduced for treatment of mild-to-moderate COVID-19 in high-risk patients. The aim of this study is the evaluation of their effectiveness and tolerability in a real-life setting. A single-center observational study was set up, with the involvement of 1118 patients, with complete follow-up data, treated between the 5th of January and the 3rd of October 2022 at Santa Maria Goretti's hospital in Latina, Central Italy. A univariable and a multivariable analysis were performed on clinical and demographic data and composite outcome, the persistence of symptoms at 30 days and time to negativization, respectively. The three antivirals showed a similar effectiveness in containing the progression of the infection to severe COVID-19 and a good tolerability in the absence of serious adverse effects. Persistence of symptoms after 30 days was more common in females than males and less common in patients treated with molnupiravir and nirmatrelvir/r. The availability of different antiviral molecules is a strong tool and, if correctly prescribed, they can have a significant role in changing the natural history of infection for frail persons, in which vaccination could be not sufficient for the prevention of severe COVID-19.