Detalhe da pesquisa
1.
Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades.
J Biol Chem
; 294(33): 12330-12338, 2019 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31197039
2.
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure.
J Biol Chem
; 292(35): 14371-14380, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28684416
3.
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling.
Proc Natl Acad Sci U S A
; 110(33): 13398-403, 2013 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23901112
4.
Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ.
Blood
; 119(19): 4499-511, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22438257
5.
Targeting density-enhanced phosphatase-1 (DEP-1) with antisense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice.
Cell Commun Signal
; 11: 49, 2013 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23889985
6.
12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases.
Proc Natl Acad Sci U S A
; 107(36): 15774-9, 2010 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20798033
7.
Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases.
Am J Respir Crit Care Med
; 183(8): 1092-102, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177885
8.
Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation.
Elife
; 112022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35587260
9.
Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H2O2 Together with Bicarbonate.
Antioxidants (Basel)
; 10(1)2021 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33466723
10.
FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Cancer Res
; 67(19): 9006-12, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17909001
11.
The A to Z of modulated cell patterning by mammalian thioredoxin reductases.
Free Radic Biol Med
; 115: 484-496, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29278740
12.
Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2.
Free Radic Biol Med
; 43(1): 100-10, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17561098
13.
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Antioxid Redox Signal
; 22(11): 938-50, 2015 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25647640
14.
Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration.
Antioxid Redox Signal
; 20(13): 1994-2010, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24111825
15.
The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation.
Free Radic Biol Med
; 68: 268-77, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24378437
16.
Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats.
J Mol Med (Berl)
; 92(9): 983-94, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24858946
17.
Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases.
Cell Signal
; 23(5): 820-6, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21241797
18.
Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.
J Biol Chem
; 279(23): 24152-62, 2004 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15056668