Detalhe da pesquisa
1.
Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
Bioorg Med Chem
; 32: 115995, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33477021
2.
Machine Learning Platform to Discover Novel Growth Inhibitors of Neisseria gonorrhoeae.
Pharm Res
; 37(7): 141, 2020 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661900
3.
Synthesis and biological evaluation of semi-synthetic albocycline analogs.
Bioorg Med Chem Lett
; 30(21): 127509, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32827630
4.
Synthesis and biological evaluation of solithromycin analogs against multidrug resistant pathogens.
Bioorg Med Chem Lett
; 29(11): 1386-1389, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962084
5.
Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry.
J Am Chem Soc
; 138(9): 3136-44, 2016 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26878192
6.
Mycobacterium tuberculosis KasA as a drug target: Structure-based inhibitor design.
Front Cell Infect Microbiol
; 12: 1008213, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36189349
7.
Alternative approaches utilizing click chemistry to develop next-generation analogs of solithromycin.
Eur J Med Chem
; 233: 114213, 2022 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35240514
8.
Rickettsia Aglow: A Fluorescence Assay and Machine Learning Model to Identify Inhibitors of Intracellular Infection.
ACS Infect Dis
; 8(7): 1280-1290, 2022 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35748568
9.
Synthesis, Biological Evaluation, and Computational Analysis of Biaryl Side-Chain Analogs of Solithromycin.
ChemMedChem
; 16(21): 3368-3373, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355515
10.
Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection.
PLoS One
; 16(5): e0249841, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33939697
11.
Bayesian Modeling and Intrabacterial Drug Metabolism Applied to Drug-Resistant Staphylococcus aureus.
ACS Infect Dis
; 7(8): 2508-2521, 2021 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34342426
12.
Ribosome-Templated Azide-Alkyne Cycloadditions Using Resistant Bacteria as Reaction Vessels: in Cellulo Click Chemistry.
ACS Med Chem Lett
; 9(9): 907-911, 2018 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30258539