RESUMO
A facile and efficient strategy to synthesize substituted thiazoles via a cascade reaction from chromone derivatives and thioamides in an environmentally benign medium was developed. This cascade reaction involves a Michael addition/intramolecular cyclization process and a broad scope of reversed regioselectivity products was prepared in a short reaction time with excellent yields. The reversed regioselectivity was also explained by DFT calculations.
RESUMO
Correction for 'Regioselective synthesis of substituted thiazoles via cascade reactions from 3-chlorochromones and thioamides' by Tianzi Dai et al., Org. Biomol. Chem., 2020, 18, 6162-6170, DOI: .
RESUMO
A facile and efficient synthetic strategy for the chemoselective synthesis of monocyclic/tricyclic-fused pyrazoles was developed, and it was oriented by different 3-position substituents (H or Cl) on the chromones. The reaction proceeded in a one-pot sequential way with a broad substrate scope and moderate to excellent yields.