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1.
J Pak Med Assoc ; 71(8): 2083-2086, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34418036

RESUMO

Papillary thyroid carcinoma (PTC) is the most common type of all thyroid carcinomas and accounts for up to 90% of all thyroid malignancies. It is the most indolent form of the disease and has an excellent prognosis. On the other hand, Primary thyroid lymphoma (PTL) is a rare entity accounting for only about 1% to 5% of all thyroid malignancies and only 2% of extranodal lymphomas. Synchronous PTC and PTL is a very rare condition and only a few cases have been reported in the literature up till now. We report one such case in a 52-year-old lady who was referred to us with goiter and progressively increasing difficulty in breathing.


Assuntos
Carcinoma Papilar , Linfoma Difuso de Grandes Células B , Neoplasias da Glândula Tireoide , Feminino , Humanos , Linfoma Difuso de Grandes Células B/diagnóstico , Pessoa de Meia-Idade , Prognóstico , Câncer Papilífero da Tireoide
2.
J Pak Med Assoc ; 71(7): 1893-1896, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34410269

RESUMO

External auditory canal, like other epithelialized surfaces is predisposed to malignancies such as Squamous cell carcinomas (SCC), melanomas and adenocarcinomas. In this background, malignancies like adenoid cystic carcinoma (ACC) are a rare occurrence and need to be thoroughly evaluated both locally and for distant extension. The malignancy needs to be addressed with an aggressive approach surgically with adequate marginal clearance. The role of radiation is debatable considering the outcomes in the limited data. Here we present the case of a 35-year-old female who came in with otalgia and otorrhea associated with a mass in the external auditory canal. After biopsy and imaging, a diagnosis of adenoid cystic carcinoma was made and the patient was managed accordingly.


Assuntos
Carcinoma Adenoide Cístico , Neoplasias da Orelha , Adulto , Carcinoma Adenoide Cístico/diagnóstico por imagem , Carcinoma Adenoide Cístico/cirurgia , Meato Acústico Externo/diagnóstico por imagem , Neoplasias da Orelha/diagnóstico por imagem , Neoplasias da Orelha/cirurgia , Dor de Orelha , Feminino , Humanos , Doenças Raras
3.
J Pak Med Assoc ; 70(6): 1086-1089, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32810114

RESUMO

Right recurrent laryngeal nerve can take a "Non-Recurrent" course and can present as a Non Recurrent Laryngeal nerve which is a rare entity. Such anomalies can lead to difficulty in locating the laryngeal nerve during thyroid surgeries and there are higher chances of it being injured. Therefore, surgeons should be mindful of this entity. We report the case of a 53-year-old lady who underwent thyroid surgery and a right Non Recurrent Laryngeal Nerve was identified intra-operatively.


Assuntos
Cirurgiões , Tireoidectomia , Feminino , Humanos , Nervos Laríngeos , Pessoa de Meia-Idade , Nervo Laríngeo Recorrente , Glândula Tireoide/diagnóstico por imagem , Glândula Tireoide/cirurgia
4.
J Pak Med Assoc ; 70(Suppl 1)(2): S60-S64, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31981338

RESUMO

Laryngotracheal trauma is rare but can pose serious threats to one's life. Presenting symptoms vary according to the severity of injury. Immediate Airway control is first step in the management, intubation should be considered by a senior member of the trauma team if the injury is minor while tracheostomy should be reserved for more severe injuries. Evaluation by a fibre-optic laryngoscopy and CT scan should be done whenever possible. Reconstruction is done according to the site involved using suture, titanium miniplates and stents. Tissue engineering has added a new horizon in this management but up till now complete laryngotracheal regeneration is very far-fetched, but tissue regeneration at individual sites have shown some positive results. More work needs to be done in this less explored field including laryngeal transplantation.


Assuntos
Tratamento Conservador , Fraturas de Cartilagem/terapia , Lacerações/terapia , Edema Laríngeo/terapia , Laringe/lesões , Procedimentos de Cirurgia Plástica , Traqueia/lesões , Manuseio das Vias Aéreas/métodos , Terapia Baseada em Transplante de Células e Tecidos , Disfonia/etiologia , Dispneia/etiologia , Esofagoscopia , Fraturas de Cartilagem/complicações , Hemoptise/etiologia , Humanos , Peptídeos e Proteínas de Sinalização Intercelular/uso terapêutico , Lacerações/complicações , Cartilagens Laríngeas/lesões , Edema Laríngeo/etiologia , Laringoscopia , Lesões do Pescoço/complicações , Lesões do Pescoço/terapia , Sons Respiratórios/etiologia , Stents , Enfisema Subcutâneo , Traumatismos Torácicos/complicações , Traumatismos Torácicos/terapia , Alicerces Teciduais , Tomografia Computadorizada por Raios X , Traqueostomia , Paralisia das Pregas Vocais/etiologia
5.
Front Psychol ; 13: 961400, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36186294

RESUMO

One of the goals of happiness research is to identify the key factors that influence it. Therefore, the present research is designed to examine the determining factors of subjective wellbeing (SWB) in Pakistan. The present research is conducted by collecting the data of 1,566 households in Punjab, Pakistan, using the ordered logit and tobit model. The findings of this research confirm that income, education, government effectiveness, no perceived corruption, and perceived institutional quality improve wellbeing, while lower trust in family and friends, poor health status, living on rent, and dissatisfaction with the services of hospitals lower the level of wellbeing. But individuals with more social ties, who face barriers in health services, live more happily satisfied with their lives. Crime victimization and worrisome terrorism also lower the level of SWB. Findings of research strongly emphasize policymakers and government institutions to improve their quality and take essential measures for improving the governance structure.

6.
J Ayub Med Coll Abbottabad ; 34(Suppl 1)(3): S730-S732, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36414604

RESUMO

A fibroepithelial polyp is a benign polypoidal lesion of mesodermal origin. It can present in any area of the body with an epithelial surface. These are relatively more common in skin and genitourinary tract and has been reported very rarely in head and neck region. We report here a rare presentation of fibroepithelial polyp in sinonasal cavity presenting with the symptoms of unilateral nasal obstruction. The patient underwent endoscopic surgical excision and recovered completely. In patients with unilateral sinonasal growing masses fibroepithelial polyp should be considered as one of the possible diagnoses. Sinonasal fibroepithelial polyps have good prognosis after being treated surgically.


Assuntos
Neoplasias Cutâneas , Humanos , Pele , Cabeça , Pescoço , Peso Molecular
7.
BMJ Case Rep ; 14(5)2021 May 24.
Artigo em Inglês | MEDLINE | ID: mdl-34031060

RESUMO

Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon soft-tissue malignancy. LGFMS preferentially affects trunks and extremities of young adults; however, occasional cases have been reported in different sites of head and neck region including oral cavity, larynx and oropharynx. LGFMS usually exhibit areas of collagenised and myxoid stroma with appearance of spindle cells in whorling pattern. It is a challenge to diagnose it accurately as most of the time it is misdiagnosed as benign neoplastic entity of spindle cells. There have been only few isolated cases of LGFMS reported in head and neck region and LGFMS originating from the parapharyngeal space has never been reported before. We recently experienced a case of low grade fibomyxoid sarcoma in parapharyngeal space of neck. LGFMS have the propensity to locally recur and to metastasise. Due to its rarity in head and neck region, there are no well-established treatment and follow-up guidelines.


Assuntos
Fibrossarcoma , Mixossarcoma , Sarcoma , Neoplasias de Tecidos Moles , Fibrossarcoma/diagnóstico , Fibrossarcoma/cirurgia , Humanos , Recidiva Local de Neoplasia , Espaço Parafaríngeo , Sarcoma/diagnóstico por imagem , Adulto Jovem
8.
BMJ Case Rep ; 13(6)2020 Jun 21.
Artigo em Inglês | MEDLINE | ID: mdl-32565439

RESUMO

Preserving the spinal accessory nerve (SAN) is an important step in the modern-day neck dissection to avoid postoperative functional morbidity in patients. This goal can become technically difficult, especially, when rare anatomical variations are encountered. We present a case of dual SAN in a patient undergoing selective neck dissection for oral squamous cell carcinoma. Both SANs were preserved and patient had no shoulder dysfunction postoperatively. We take this opportunity to emphasise that meticulous dissection is the only proven way to preserve the nerve. And that surgeons should be aware of this anatomical variation. SAN should be subjected to minimal traction during neck dissection to avoid tension neuropraxia and long-term shoulder dysfunction.


Assuntos
Traumatismos do Nervo Acessório/prevenção & controle , Nervo Acessório/cirurgia , Esvaziamento Cervical/métodos , Complicações Pós-Operatórias/prevenção & controle , Ombro/inervação , Traumatismos do Nervo Acessório/etiologia , Variação Anatômica , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Esvaziamento Cervical/efeitos adversos , Complicações Pós-Operatórias/etiologia , Carcinoma de Células Escamosas de Cabeça e Pescoço/cirurgia
9.
BMJ Case Rep ; 13(4)2020 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-32327463

RESUMO

Malignant peripheral nerve sheath tumours of thyroid are rare entities that can present a diagnostic dilemma. We present the case of a patient who presented with neck mass with a history of multiple neck surgeries and airway compression. The patient's previous histopathology was mistaken for Riedel's thyroiditis in an outside hospital, which delayed appropriate treatment leading to suffering on part of the patient and frustration on part of the physician. We emphasise that rare malignancies should be considered in rapidly growing neck masses that are causing airway compression, and histopathology of such tumours should be reported by expert pathologists.


Assuntos
Neoplasias de Bainha Neural/diagnóstico , Neoplasias da Glândula Tireoide/diagnóstico , Adulto , Obstrução das Vias Respiratórias/etiologia , Meios de Contraste , Diagnóstico Diferencial , Feminino , Humanos , Neoplasias de Bainha Neural/patologia , Neoplasias de Bainha Neural/terapia , Neoplasias da Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/terapia , Tireoidectomia , Tomografia Computadorizada por Raios X , Traqueostomia
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