Detalhe da pesquisa
1.
Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase.
Proc Natl Acad Sci U S A
; 120(42): e2303690120, 2023 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37819980
2.
The primary familial brain calcification-associated protein MYORG is an α-galactosidase with restricted substrate specificity.
PLoS Biol
; 20(9): e3001764, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36129849
3.
Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.
Proc Natl Acad Sci U S A
; 119(4)2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35074914
4.
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.
Proc Natl Acad Sci U S A
; 119(31): e2203167119, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35881786
5.
Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases.
J Biol Chem
; 299(11): 105338, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37838169
6.
Molecular Basis for Inhibition of Heparanases and ß-Glucuronidases by Siastatin B.
J Am Chem Soc
; 146(1): 125-133, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38118176
7.
Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining α-Glucosidase Inhibition.
Chemistry
; : e202400723, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38623783
8.
Capture-and-release of a sulfoquinovose-binding protein on sulfoquinovose-modified agarose.
Org Biomol Chem
; 22(16): 3237-3244, 2024 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38567495
9.
Detection of Sulfoquinovosidase Activity in Cell Lysates Using Activity-Based Probes.
Angew Chem Int Ed Engl
; : e202401358, 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38647177
10.
Widespread Family of NAD+-Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism.
J Am Chem Soc
; 145(51): 28216-28223, 2023 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38100472
11.
Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, ß-Glucuronidase and Heparanase.
Chembiochem
; 24(4): e202200619, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36453606
12.
The development of a broad-spectrum retaining ß-exo-galactosidase activity-based probe.
Org Biomol Chem
; 21(38): 7813-7820, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37724332
13.
Complex pectin metabolism by gut bacteria reveals novel catalytic functions.
Nature
; 544(7648): 65-70, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28329766
14.
Corrigendum: Complex pectin metabolism by gut bacteria reveals novel catalytic functions.
Nature
; 548(7669): 612, 2017 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29411780
15.
Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc Natl Acad Sci U S A
; 117(47): 29595-29601, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154157
16.
Mechanistic basis of substrate-O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study.
Proc Natl Acad Sci U S A
; 117(32): 19178-19189, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723819
17.
Potent De Novo Macrocyclic Peptides That Inhibit O-GlcNAc Transferase through an Allosteric Mechanism.
Angew Chem Int Ed Engl
; 62(5): e202215671, 2023 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460613
18.
Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications.
J Am Chem Soc
; 144(2): 832-844, 2022 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34985906
19.
1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease.
J Am Chem Soc
; 144(32): 14819-14827, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917590
20.
Structural perturbations of substrate binding and oxidation state changes in a lytic polysaccharide monooxygenase.
J Biol Inorg Chem
; 27(8): 705-713, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36208326