Detalhe da pesquisa
1.
Silmitasertib plus gemcitabine and cisplatin first-line therapy in locally advanced/metastatic cholangiocarcinoma: A Phase 1b/2 study.
Hepatology
; 77(3): 760-773, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152015
2.
ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.
BMC Cancer
; 22(1): 1107, 2022 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36309653
3.
Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities.
Curr Treat Options Oncol
; 23(12): 1793-1803, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36417147
4.
A phase 1b dose escalation study of Wnt pathway inhibitor vantictumab in combination with nab-paclitaxel and gemcitabine in patients with previously untreated metastatic pancreatic cancer.
Invest New Drugs
; 38(3): 821-830, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31338636
5.
A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.
Oncologist
; 23(12): 1409-e140, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30139840
6.
A Phase Ib Expansion Cohort Evaluating Aurora A Kinase Inhibitor Alisertib and Dual TORC1/2 Inhibitor Sapanisertib in Patients with Advanced Solid Tumors.
Cancers (Basel)
; 16(8)2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672538
7.
First-in-Human Dose-Escalation Study of the Novel Oral Depsipeptide Class I-Targeting HDAC Inhibitor Bocodepsin (OKI-179) in Patients with Advanced Solid Tumors.
Cancers (Basel)
; 16(1)2023 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38201519
8.
WEE1 Inhibition in Combination With Targeted Agents and Standard Chemotherapy in Preclinical Models of Pancreatic Ductal Adenocarcinoma.
Front Oncol
; 11: 642328, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33869031
9.
Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers.
Front Oncol
; 11: 614640, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33777751
10.
Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers.
J Clin Invest
; 131(24)2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907910
11.
Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors.
Clin Cancer Res
; 26(17): 4633-4642, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32414750
12.
Treatment delays during FOLFOX chemotherapy in patients with colorectal cancer: a multicenter retrospective analysis.
J Gastrointest Oncol
; 10(5): 841-846, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31602321
13.
Association of Cancer Immunotherapy With Acute Macular Neuroretinopathy and Diffuse Retinal Venulitis.
JAMA Ophthalmol
; 137(1): 96-100, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30383154
14.
Phase I Study of the Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Navoximod (GDC-0919) Administered with PD-L1 Inhibitor (Atezolizumab) in Advanced Solid Tumors.
Clin Cancer Res
; 25(11): 3220-3228, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770348
15.
Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.
Cancer Res
; 78(18): 5398-5407, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30042150
16.
Patterns of Care for Locally Advanced Pancreatic Adenocarcinoma Using the National Cancer Database.
Pancreas
; 46(7): 904-912, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28697131
17.
Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Oncotarget
; 7(31): 50290-50301, 2016 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27385211
18.
Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
Mol Cancer Ther
; 14(2): 317-25, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25376610
19.
Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.
Front Pharmacol
; 6: 120, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26136684
20.
Targeting nuclear kinases in cancer: development of cell cycle kinase inhibitors.
Pharmacol Ther
; 142(2): 258-69, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362082