Detalhe da pesquisa
1.
Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations.
Angew Chem Int Ed Engl
; 59(34): 14481-14489, 2020 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510788
2.
Proteome-scale Binary Interactomics in Human Cells.
Mol Cell Proteomics
; 15(12): 3624-3639, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27803151
3.
Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor.
Angew Chem Int Ed Engl
; 57(36): 11629-11633, 2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29978938
4.
Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor.
Mol Cell Proteomics
; 13(12): 3332-42, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25154561
5.
Alternative reagents for methotrexate as immobilizing anchor moieties in the optimization of MASPIT: synthesis and biological evaluation.
Chembiochem
; 16(5): 834-43, 2015 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25688755
6.
Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors.
Nat Commun
; 13(1): 2530, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534503
7.
Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors.
ACS Med Chem Lett
; 10(11): 1549-1553, 2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749909
8.
Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor.
Cancer Discov
; 9(7): 926-943, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092401
9.
Chemical Dimerizers in Three-Hybrid Systems for Small Molecule-Target Protein Profiling.
ACS Chem Biol
; 11(8): 2075-90, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27267544
10.
A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT.
ChemMedChem
; 8(3): 521-6, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23341183