Detalhe da pesquisa
1.
Discovery of highly potent HDAC8 PROTACs with anti-tumor activity.
Bioorg Chem
; 136: 106546, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37098288
2.
Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury.
Cell Mol Life Sci
; 79(2): 105, 2022 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091838
3.
Rational Design in Photopharmacology with Molecular Photoswitches.
Angew Chem Int Ed Engl
; 62(30): e202300681, 2023 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37026576
4.
Histone Deacetylase 3-Directed PROTACs Have Anti-inflammatory Potential by Blocking Polarization of M0-like into M1-like Macrophages.
Angew Chem Int Ed Engl
; 62(42): e202310059, 2023 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638390
5.
4-Iodopyrimidine Labeling Reveals Nuclear Translocation and Nuclease Activity for Both MIF and MIF2.
Chemistry
; 28(1): e202103030, 2022 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724273
6.
Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing.
Nucleic Acids Res
; 48(2): 517-532, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31799598
7.
Adsorptive Microtiter Plates As Solid Supports in Affinity Purification Workflows.
J Proteome Res
; 20(11): 5218-5221, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669399
8.
Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs.
J Biol Chem
; 295(3): 850-867, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31811089
9.
Combined Metabolic and Chemical (CoMetChem) Labeling Using Stable Isotopes-a Strategy to Reveal Site-Specific Histone Acetylation and Deacetylation Rates by LC-MS.
Anal Chem
; 93(38): 12872-12880, 2021 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34519498
10.
HDAC/MIF dual inhibitor inhibits NSCLC cell survival and proliferation by blocking the AKT pathway.
Bioorg Chem
; 117: 105396, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34649152
11.
Identification of a Bromodomain-like Region in 15-Lipoxygenase-1 Explains Its Nuclear Localization.
Angew Chem Int Ed Engl
; 60(40): 21875-21883, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34388301
12.
Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells.
Angew Chem Int Ed Engl
; 60(32): 17514-17521, 2021 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34018657
13.
Development of phenylthiourea derivatives as allosteric inhibitors of pyoverdine maturation enzyme PvdP tyrosinase.
Bioorg Med Chem Lett
; 30(17): 127409, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738979
14.
HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.
J Cell Physiol
; 233(1): 530-548, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28300292
15.
High yield production of human invariant chain CD74 constructs fused to solubility-enhancing peptides and characterization of their MIF-binding capacities.
Protein Expr Purif
; 148: 46-53, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29601965
16.
Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.
Bioorg Med Chem
; 26(5): 999-1005, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29428527
17.
The Process and Strategy for Developing Selective Histone Deacetylase 3 Inhibitors.
Molecules
; 23(3)2018 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29498635
18.
A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices.
Pulm Pharmacol Ther
; 44: 88-95, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28323055
19.
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity.
Bioorg Med Chem
; 25(3): 847-856, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989416
20.
Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions.
Pharmacol Rev
; 65(2): 670-709, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23447132