Detalhe da pesquisa
1.
N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration.
Matrix Biol
; 70: 84-101, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572155
2.
HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model.
EBioMedicine
; 27: 258-274, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269042
3.
HtrA1 activation is driven by an allosteric mechanism of inter-monomer communication.
Sci Rep
; 7(1): 14804, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29093542
4.
Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery.
Cell Chem Biol
; 24(5): 624-634.e3, 2017 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28434878
5.
Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance.
Eur J Pharm Biopharm
; 63(3): 347-55, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16621491
6.
Impact of serum on clearance predictions obtained from suspensions and primary cultures of rat hepatocytes.
Eur J Pharm Sci
; 23(2): 189-99, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15451007
7.
Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells.
Cell Rep
; 9(3): 810-21, 2014 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25437537