Detalhe da pesquisa
1.
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Blood
; 126(11): 1346-56, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186940
2.
Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses.
Res Sq
; 2023 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865338
3.
Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia.
Blood
; 115(20): 4051-60, 2010 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20110419
4.
Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome.
Cancer Res
; 67(13): 6383-91, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17616698
5.
Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer.
Front Oncol
; 9: 686, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31428575
6.
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.
Cancer Cell
; 33(5): 905-921.e5, 2018 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29763624
7.
Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.
Cell Rep
; 18(3): 601-610, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099841
8.
Drug discovery in the ubiquitin regulatory pathway.
Drug Discov Today
; 8(16): 746-54, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12944097
9.
Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Mol Cancer Ther
; 13(4): 890-901, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24523301
10.
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity.
Chem Biol
; 19(12): 1535-45, 2012 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142757
11.
Molecular mechanisms of bortezomib resistant adenocarcinoma cells.
PLoS One
; 6(12): e27996, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22216088
12.
Cellular localization and antiproliferative effect of peptides discovered from a functional screen of a retrovirally delivered random peptide library.
Chem Biol
; 10(10): 975-87, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14583264
13.
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.
Nat Med
; 15(7): 781-7, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19525961
14.
Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047).
J Med Chem
; 52(9): 3028-38, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19348473
15.
Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma.
Blood
; 110(9): 3281-90, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17591945
16.
Cell cycle regulatory E3 ubiquitin ligases as anticancer targets.
Drug Resist Updat
; 5(6): 249-58, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12531181