Detalhe da pesquisa
1.
Amine coupling versus biotin capture for the assessment of sulfonamide as ligands of hCA isoforms.
Anal Biochem
; 511: 42-51, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27485269
2.
Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors.
Bioorg Med Chem
; 23(22): 7340-7, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526740
3.
Label-free characterization of carbonic anhydrase-novel inhibitor interactions using surface plasmon resonance, isothermal titration calorimetry and fluorescence-based thermal shift assays.
J Mol Recognit
; 27(1): 46-56, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375583
4.
New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides.
Bioorg Med Chem
; 21(6): 1451-64, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23168081
5.
Impact of aryloxy-linked quinazolines: a novel series of selective VEGFR-2 receptor tyrosine kinase inhibitors.
Bioorg Med Chem Lett
; 21(7): 2106-12, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21353546
6.
Preparative enantiomeric separation of new selective CB2 receptor agonists by liquid chromatography on polysaccharide-based chiral stationary phases: determination of enantiomeric purity and assignment of absolute stereochemistry by X-ray structure analysis.
Chirality
; 23(5): 389-96, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21433091
7.
Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors.
Bioorg Med Chem
; 18(21): 7392-401, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20880712
8.
Quinazoline-urea, new protein kinase inhibitors in treatment of prostate cancer.
J Enzyme Inhib Med Chem
; 25(2): 158-71, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20222760
9.
Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells.
Mol Cancer Ther
; 6(3): 967-78, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17363490
10.
Pharmacomodulations around the 4-oxo-1,4-dihydroquinoline-3-carboxamides, a class of potent CB2-selective cannabinoid receptor ligands: consequences in receptor affinity and functionality.
J Med Chem
; 50(22): 5471-84, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17915849
11.
DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge.
Biomolecules
; 7(1)2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28067760
12.
Chiral separation of new sulfonamide derivatives and evaluation of their enantioselective affinity for human carbonic anhydrase II by microscale thermophoresis and surface plasmon resonance.
J Pharm Biomed Anal
; 137: 113-122, 2017 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28110167
13.
Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.
J Med Chem
; 49(1): 70-9, 2006 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16392793
14.
New antiproliferative benzoindolinothiazepines derivatives.
Eur J Med Chem
; 40(2): 167-72, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15694651
15.
Quinazoline derivatives as anticancer drugs: a patent review (2011 - present).
Expert Opin Ther Pat
; 25(7): 789-804, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25910402
16.
Inhibition of tumor cell growth and angiogenesis by 7-aminoalkoxy-4-aryloxy-quinazoline ureas, a novel series of multi-tyrosine kinase inhibitors.
Eur J Med Chem
; 79: 369-81, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747748
17.
Synthesis and structure-activity relationships of (aryloxy)quinazoline ureas as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors.
J Med Chem
; 55(3): 1189-204, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22229669
18.
Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.
Mol Cancer Ther
; 9(3): 617-30, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20179163
19.
Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives.
J Med Chem
; 53(22): 8089-103, 2010 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21033670
20.
Novel combination therapy against metastatic and androgen-independent prostate cancer by using gefitinib, tamoxifen and etoposide.
Int J Cancer
; 120(1): 160-9, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17013895