Detalhe da pesquisa
1.
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Cell
; 177(3): 572-586.e22, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30955884
2.
The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.
Development
; 150(9)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37082953
3.
Transcriptional control of leukemogenesis by the chromatin reader SGF29.
Blood
; 143(8): 697-712, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38048593
4.
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
J Biol Chem
; 298(1): 101477, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34896393
5.
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
Mol Cancer
; 22(1): 196, 2023 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38049829
6.
A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML.
Blood
; 137(24): 3403-3415, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33690798
7.
The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol Cell
; 60(2): 319-27, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26439302
8.
Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis.
Gastroenterology
; 159(5): 1882-1897.e5, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32768595
9.
Silencing with SAFB: a new role for HOXA9 in AML.
Blood
; 141(14): 1653-1655, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37022737
10.
The role of TP53 in acute myeloid leukemia: Challenges and opportunities.
Genes Chromosomes Cancer
; 58(12): 875-888, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31393631
11.
Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus.
Blood
; 129(3): 319-323, 2017 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27827825
12.
Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
Blood
; 121(13): 2533-41, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23361907
13.
Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.
Trends Immunol
; 33(11): 563-70, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22867873
14.
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.
Cancer Cell
; 10(5): 363-74, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17097559
15.
SRX3177, a CDK4/6-PI3K-BET inhibitor, in combination with an RdRp inhibitor, Molnupiravir, or an entry inhibitor MU-UNMC-2, has potent antiviral activity against the Omicron variant of SARS-CoV-2.
Antiviral Res
; 227: 105904, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38729306
16.
Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
Blood Adv
; 8(8): 2005-2017, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38306602
17.
Therapeutic targeting of leukemia stem cells in acute myeloid leukemia.
Front Oncol
; 13: 1204895, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37601659
18.
DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity.
Stem Cell Reports
; 18(12): 2451-2463, 2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37995701
19.
Detection of TP53 Mutation in Acute Myeloid Leukemia by RT-PCR-Based Sanger Sequencing.
Methods Mol Biol
; 2594: 87-95, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36264490
20.
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.
Nat Genet
; 55(12): 2189-2199, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945900