Detalhe da pesquisa
1.
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury.
Nature
; 618(7967): 1072-1077, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196676
2.
Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.
Nature
; 571(7764): 284-288, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31263273
3.
Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol Cell
; 68(2): 431-445.e5, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033322
4.
Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
PLoS Biol
; 19(4): e3001191, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33886552
5.
RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.
Mol Cell
; 64(5): 951-966, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27889450
6.
The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
EMBO J
; 38(20): e101744, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515872
7.
The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
EMBO J
; 39(1): e103976, 2020 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31894584
8.
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Nat Struct Mol Biol
; 31(4): 667-677, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326651
9.
Docking for EP4R antagonists active against inflammatory pain.
Nat Commun
; 14(1): 8067, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38057319
10.
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
bioRxiv
; 2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292845
11.
Biochemical Assays to Directly Assess Smoothened Activation by a Conformationally Sensitive Nanobody.
Methods Mol Biol
; 2374: 149-160, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34562250
12.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Sci Adv
; 7(16)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33853786
13.
EpCAM-Mediated Cellular Plasticity Promotes Radiation Resistance and Metastasis in Breast Cancer.
Front Cell Dev Biol
; 8: 597673, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33490064
14.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
bioRxiv
; 2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33269349
15.
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science
; 370(6523): 1473-1479, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154106
16.
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.
bioRxiv
; 2020 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817938