RESUMO
Fungal infections are a subset of infectious processes that an otolaryngologist is required to be familiar with. They can be encountered in otology, rhinology and head and neck surgery. The presence of fungal rhinosinusitis is well recognised by otolaryngologists, but the classifications and appropriate management are not so well understood. The prevalence of fungal sinus disease is thought to be have been increasing in recent decades There is speculation that this may be due to increased awareness, antibiotic overuse and increased use of immunosuppressant medications. Added to this, there has been a large amount published on the role of fungi as a causative organism in chronic rhinosinusitis. Given the importance of fungal rhinosinusitis in clinical practice, we aim to review the classification and current management strategies based on up-to-date literature.
Assuntos
Micoses/complicações , Rinite/etiologia , Sinusite/etiologia , Antifúngicos/uso terapêutico , Humanos , Infecções Fúngicas Invasivas/complicações , Infecções Fúngicas Invasivas/tratamento farmacológico , Micoses/tratamento farmacológico , Rinite/tratamento farmacológico , Sinusite/tratamento farmacológicoRESUMO
Epirubicin is an anthracycline chemotherapy agent used for treatment of several cancers including oesophageal, breast and gastric. Extravasation is a well-recognised and serious complication of any intravenous therapies but especially chemotherapeutic agents. Signs of the injury can be subtle and without prompt recognition and treatment there can be extensive tissue damage and depending on location of injury this can result in significant functional loss. In this article, a case of delayed management of epirubicin extravasation from a cannula situated at the dorsum of the hand is discussed. Successful surgical reconstruction of the resulting substantial tissue damage using a radial forearm flap 21â days following injury is described.
Assuntos
Antibióticos Antineoplásicos/efeitos adversos , Epirubicina/efeitos adversos , Extravasamento de Materiais Terapêuticos e Diagnósticos/cirurgia , Assistência ao Convalescente , Idoso , Antibióticos Antineoplásicos/administração & dosagem , Epirubicina/administração & dosagem , Neoplasias Esofágicas , Extravasamento de Materiais Terapêuticos e Diagnósticos/etiologia , Feminino , Mãos/cirurgia , Humanos , Procedimentos de Cirurgia Plástica , Transplante de Pele/métodos , Retalhos Cirúrgicos , Resultado do TratamentoRESUMO
We present a case of a 62-year-old man with a lipoma in the exceedingly rare location of the larynx, causing intermittent airway obstruction and dysphagia. The lipoma was excised endoscopically with complete resolution of symptoms. Lipomas are relatively common, accounting for 4-5% of all benign tumours in the body. They traditionally occur in areas of large depositions of subcutaneous fat, most frequently the trunk and limbs. They are recognised to occur in the head and neck but these only represent 13-15% of all lipomas. Lipomas are typically asymptomatic unless their impingement of nearby structures causes symptoms.