Detalhe da pesquisa
1.
Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway.
J Biol Chem
; 287(21): 17618-17627, 2012 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22467872
2.
Induction of CFTR gene expression by 1,25(OH)2 vitamin D3, 25OH vitamin D3, and vitamin D3 in cultured human airway epithelial cells and in mouse airways.
J Steroid Biochem Mol Biol
; 173: 323-332, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28130182
3.
Potent in vitro and in vivo antifungal activity of a small molecule host defense peptide mimic through a membrane-active mechanism.
Sci Rep
; 7(1): 4353, 2017 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659617
4.
LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes.
Leuk Res
; 39(6): 649-56, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25850729
5.
Leukotoxin kills rodent WBC by targeting leukocyte function associated antigen 1.
Comp Med
; 63(4): 331-7, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24209968