Detalhe da pesquisa
1.
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
FASEB J
; 35(2): e21156, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33140449
2.
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
Crit Care Med
; 47(11): e919-e929, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31389840
3.
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Crit Care
; 23(1): 355, 2019 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31722736
4.
The post-septic peripheral myeloid compartment reveals unexpected diversity in myeloid-derived suppressor cells.
Front Immunol
; 15: 1355405, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720891
5.
Sex differences associate with late microbiome alterations after murine surgical sepsis.
J Trauma Acute Care Surg
; 93(2): 137-146, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35324554
6.
A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.
Front Immunol
; 12: 696536, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34484194
7.
Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice.
Shock
; 55(4): 519-525, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32826817
8.
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Shock
; 55(5): 587-595, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33021571
9.
Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agouti-related protein antagonist.
Biochemistry
; 49(22): 4583-600, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20462274
10.
The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm.
Bioorg Med Chem
; 18(2): 580-9, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20056544
11.
Semi-rigid tripeptide agonists of melanocortin receptors.
Bioorg Med Chem Lett
; 19(17): 5176-81, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19635667
12.
Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults.
PLoS One
; 13(10): e0205327, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30300408
13.
Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis.
Shock
; 49(3): 249-258, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28885387
14.
Human ß-Defensin 1 and ß-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors.
J Med Chem
; 61(8): 3738-3744, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29578343
15.
Synthesis and Structure-Activity Relationships of Substituted Urea Derivatives on Mouse Melanocortin Receptors.
ACS Chem Neurosci
; 7(2): 196-205, 2016 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26645732
16.
Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity.
Free Radic Biol Med
; 74: 252-62, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24975655
17.
Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).
ACS Chem Neurosci
; 5(10): 1020-31, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25141170
18.
1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity.
J Med Chem
; 57(22): 9424-34, 2014 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25347033
19.
Incorporation of a bioactive reverse-turn heterocycle into a peptide template using solid-phase synthesis to probe melanocortin receptor selectivity and ligand conformations by 2D 1H NMR.
J Med Chem
; 54(5): 1379-90, 2011 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21306168