Detalhe da pesquisa
1.
Safety and biodistribution of XC001 (encoberminogene rezmadenovec) gene therapy in rats: a potential therapy for cardiovascular diseases.
Gene Ther
; 31(1-2): 45-55, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37592080
2.
Epicardial delivery of XC001 gene therapy for refractory angina coronary treatment (The EXACT Trial): Rationale, design, and clinical considerations.
Am Heart J
; 241: 38-49, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34224684
3.
Efficacy and Safety of Firibastat, A First-in-Class Brain Aminopeptidase A Inhibitor, in Hypertensive Overweight Patients of Multiple Ethnic Origins.
Circulation
; 140(2): 138-146, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31014072
4.
Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials.
J Hepatol
; 73(6): 1322-1332, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610115
5.
Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study.
J Hepatol
; 72(4): 613-626, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697972
6.
Trajectories of Changes in Renal Function in Patients with Acute Heart Failure.
J Card Fail
; 25(11): 866-874, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31319165
7.
Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure.
J Card Fail
; 23(3): 231-239, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27663098
8.
Identifying Subpopulations with Distinct Response to Treatment Using Plasma Biomarkers in Acute Heart Failure: Results from the PROTECT Trial : Differential Response in Acute Heart Failure.
Cardiovasc Drugs Ther
; 31(3): 281-293, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28656542
9.
Termination of Atrial Flutter and Fibrillation by K201's Metabolite M-II: Studies in the Canine Sterile Pericarditis Model.
J Cardiovasc Pharmacol
; 65(5): 494-9, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25636078
10.
Diuretic response in acute heart failure: clinical characteristics and prognostic significance.
Eur Heart J
; 35(19): 1284-93, 2014 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24585267
11.
Angiogenic Gene Therapy for Refractory Angina: Results of the EXACT Phase 2 Trial.
Circ Cardiovasc Interv
; 17(5): e014054, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38696284
12.
Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure.
N Engl J Med
; 363(15): 1419-28, 2010 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20925544
13.
EXACT Trial: Results of the Phase 1 Dose-Escalation Study.
Circ Cardiovasc Interv
; 16(8): e012997, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503661
14.
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure.
Circulation
; 124(3): 304-13, 2011 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21709064
15.
Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study.
Eur Heart J
; 32(12): 1519-34, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21388992
16.
Noninvasive measure of treatment response in non-alcoholic steatohepatitis: Insights from EMMINENCE and meta-analysis.
JGH Open
; 5(7): 740-749, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34263067
17.
Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function.
J Card Fail
; 16(1): 25-35, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20123315
18.
The effects of adenosine A(1) receptor antagonism in patients with acute decompensated heart failure and worsening renal function: the REACH UP study.
J Card Fail
; 16(9): 714-9, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20797594
19.
The effects of multiple doses of rolofylline on the single-dose pharmacokinetics of midazolam in healthy subjects.
Am J Ther
; 17(1): 53-60, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20027108
20.
Physician-determined worsening heart failure: a novel definition for early worsening heart failure in patients hospitalized for acute heart failure--association with signs and symptoms, hospitalization duration, and 60-day outcomes.
Cardiology
; 115(1): 29-36, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19844102