Detalhe da pesquisa
1.
Safety and biodistribution of XC001 (encoberminogene rezmadenovec) gene therapy in rats: a potential therapy for cardiovascular diseases.
Gene Ther
; 31(1-2): 45-55, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37592080
2.
Epicardial delivery of XC001 gene therapy for refractory angina coronary treatment (The EXACT Trial): Rationale, design, and clinical considerations.
Am Heart J
; 241: 38-49, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34224684
3.
Efficacy and Safety of Firibastat, A First-in-Class Brain Aminopeptidase A Inhibitor, in Hypertensive Overweight Patients of Multiple Ethnic Origins.
Circulation
; 140(2): 138-146, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31014072
4.
Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials.
J Hepatol
; 73(6): 1322-1332, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610115
5.
Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study.
J Hepatol
; 72(4): 613-626, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697972
6.
Trajectories of Changes in Renal Function in Patients with Acute Heart Failure.
J Card Fail
; 25(11): 866-874, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31319165
7.
Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure.
J Card Fail
; 23(3): 231-239, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27663098
8.
Identifying Subpopulations with Distinct Response to Treatment Using Plasma Biomarkers in Acute Heart Failure: Results from the PROTECT Trial : Differential Response in Acute Heart Failure.
Cardiovasc Drugs Ther
; 31(3): 281-293, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28656542
9.
Termination of Atrial Flutter and Fibrillation by K201's Metabolite M-II: Studies in the Canine Sterile Pericarditis Model.
J Cardiovasc Pharmacol
; 65(5): 494-9, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25636078
10.
Diuretic response in acute heart failure: clinical characteristics and prognostic significance.
Eur Heart J
; 35(19): 1284-93, 2014 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24585267
11.
Angiogenic Gene Therapy for Refractory Angina: Results of the EXACT Phase 2 Trial.
Circ Cardiovasc Interv
; 17(5): e014054, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38696284
12.
Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure.
N Engl J Med
; 363(15): 1419-28, 2010 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20925544
13.
EXACT Trial: Results of the Phase 1 Dose-Escalation Study.
Circ Cardiovasc Interv
; 16(8): e012997, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503661
14.
Noninvasive measure of treatment response in non-alcoholic steatohepatitis: Insights from EMMINENCE and meta-analysis.
JGH Open
; 5(7): 740-749, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34263067
15.
Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function.
J Card Fail
; 16(1): 25-35, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20123315
16.
Physician-determined worsening heart failure: a novel definition for early worsening heart failure in patients hospitalized for acute heart failure--association with signs and symptoms, hospitalization duration, and 60-day outcomes.
Cardiology
; 115(1): 29-36, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19844102
17.
The PROTECT pilot study: a randomized, placebo-controlled, dose-finding study of the adenosine A1 receptor antagonist rolofylline in patients with acute heart failure and renal impairment.
J Card Fail
; 14(8): 631-40, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18926433
18.
Improvements in signs and symptoms during hospitalization for acute heart failure follow different patterns and depend on the measurement scales used: an international, prospective registry to evaluate the evolution of measures of disease severity in acute heart failure (MEASURE-AHF).
J Card Fail
; 14(9): 777-84, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18995183
19.
Fluid overload in acute heart failure--re-distribution and other mechanisms beyond fluid accumulation.
Eur J Heart Fail
; 10(2): 165-9, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18279771
20.
Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.
Circ Heart Fail
; 11(5): e004644, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748350