Detalhe da pesquisa
1.
Dual-Programmable Semiconducting Polymer NanoPROTACs for Deep-Tissue Sonodynamic-Ferroptosis Activatable Immunotherapy.
Small
; 20(8): e2306378, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37817359
2.
Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD.
Angew Chem Int Ed Engl
; 63(12): e202315997, 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38282119
3.
Discovery of potent NAMPT-Targeting PROTACs using FK866 as the warhead.
Bioorg Med Chem Lett
; 92: 129393, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37369332
4.
Strategies for designing proteolysis targeting chimaeras (PROTACs).
Med Res Rev
; 42(3): 1280-1342, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35001407
5.
Design, Synthesis, and Structure-Activity relationships of Evodiamine-Based topoisomerase (Top)/Histone deacetylase (HDAC) dual inhibitors.
Bioorg Chem
; 122: 105702, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286923
6.
Discovery of novel tubulin inhibitors targeting the colchicine binding site via virtual screening, structural optimization and antitumor evaluation.
Bioorg Chem
; 118: 105486, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801948
7.
Structural simplification of evodiamine: Discovery of novel tetrahydro-ß-carboline derivatives as potent antitumor agents.
Bioorg Med Chem Lett
; 40: 127954, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33744440
8.
Structural Simplification of Natural Products.
Chem Rev
; 119(6): 4180-4220, 2019 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30730700
9.
Minimally invasive strategy for type I choledochal cyst in adult: combination of laparoscopy and choledochoscopy.
Surg Endosc
; 35(3): 1093-1100, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32095950
10.
Aptamer-PROTAC Conjugates (APCs) for Tumor-Specific Targeting in Breast Cancer.
Angew Chem Int Ed Engl
; 60(43): 23299-23305, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34240523
11.
Fulvic acid ameliorates drought stress-induced damage in tea plants by regulating the ascorbate metabolism and flavonoids biosynthesis.
BMC Genomics
; 21(1): 411, 2020 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32552744
12.
Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer.
Angew Chem Int Ed Engl
; 59(8): 3028-3032, 2020 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31943585
13.
Identification of pyrazolopyridine derivatives as novel spleen tyrosine kinase inhibitors.
Arch Pharm (Weinheim)
; 2018 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29952085
14.
Design, synthesis and evaluation of 4-substituted anthra[2,1-c][1,2,5]thiadiazole-6,11-dione derivatives as novel non-camptothecin topoisomerase I inhibitors.
Bioorg Med Chem Lett
; 27(9): 1929-1933, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28351590
15.
Discovery of new Syk inhibitors through structure-based virtual screening.
Bioorg Med Chem Lett
; 27(8): 1776-1779, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28268139
16.
Discovery of IDO1 and DNA dual targeting antitumor agents.
Org Biomol Chem
; 15(47): 9992-9995, 2017 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29177308
17.
Identification of benzothiophene amides as potent inhibitors of human nicotinamide phosphoribosyltransferase.
Bioorg Med Chem Lett
; 26(3): 765-768, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26755394
18.
Enantioselective organocatalytic Michael addition of isorhodanines to α,ß-unsaturated aldehydes.
Org Biomol Chem
; 14(16): 3926-33, 2016 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044054
19.
State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.
Chem Soc Rev
; 44(22): 8238-59, 2015 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248294
20.
Correction: State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.
Chem Soc Rev
; 44(22): 8375, 2015 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308471