Detalhe da pesquisa
1.
Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43321-340 peptide monomer and dimer.
Proteins
; 2023 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36841957
2.
Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex.
Biophys J
; 121(9): 1704-1714, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35364103
3.
Insights into the Atomistic Mechanisms of Phosphorylation in Disrupting Liquid-Liquid Phase Separation and Aggregation of the FUS Low-Complexity Domain.
J Chem Inf Model
; 62(13): 3227-3238, 2022 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35709363
4.
ALS-associated A315E and A315pT variants exhibit distinct mechanisms in inducing irreversible aggregation of TDP-43312-317 peptides.
Phys Chem Chem Phys
; 24(26): 16263-16273, 2022 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758309
5.
Mechanistic insight into the destabilization of p53TD tetramer by cancer-related R337H mutation: a molecular dynamics study.
Phys Chem Chem Phys
; 24(8): 5199-5210, 2022 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35166747
6.
The destructive mechanism of Aß1-42 protofibrils by norepinephrine revealed via molecular dynamics simulations.
Phys Chem Chem Phys
; 24(33): 19827-19836, 2022 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35946429
7.
Molecular mechanisms of resveratrol and EGCG in the inhibition of Aß42 aggregation and disruption of Aß42 protofibril: similarities and differences.
Phys Chem Chem Phys
; 23(34): 18843-18854, 2021 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34612422
8.
Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations.
Phys Chem Chem Phys
; 23(36): 20406-20418, 2021 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34494046
9.
Differential expression of circular RNA in patients with white matter hyperintensity and cognitive impairment. / èç½è´¨é«ä¿¡å·ä¼´è®¤ç¥åè½éç¢æ£è ç¯ç¶RNAçå·®å¼æ§è¡¨è¾¾.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
; 46(10): 1080-1089, 2021 Oct 28.
Artigo
em Inglês, Zh
| MEDLINE | ID: mdl-34911837
10.
Binding of protofibrillar Aß trimers to lipid bilayer surface enhances Aß structural stability and causes membrane thinning.
Phys Chem Chem Phys
; 19(40): 27556-27569, 2017 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28979963
11.
Fabrication of ZnS-Bi-TiO2 composites and investigation of their sunlight photocatalytic performance.
ScientificWorldJournal
; 2014: 503895, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24688396
12.
Elucidating the reversible and irreversible self-assembly mechanisms of low-complexity aromatic-rich kinked peptides and steric zipper peptides.
Nanoscale
; 16(8): 4025-4038, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38347806
13.
Deleterious nonsynonymous single nucleotide polymorphisms in human solute carriers: the first comparison of three prediction methods.
Eur J Drug Metab Pharmacokinet
; 38(1): 53-62, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22555822
14.
Interface-mediated synthesis of monodisperse ZnS nanoparticles with sulfate-reducing bacterium culture.
J Environ Sci (China)
; 25 Suppl 1: S106-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25078810
15.
Thermal-controlled cellular uptake of "hot" nanoparticles.
Nanoscale
; 15(30): 12718-12727, 2023 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37470374
16.
Membrane-Active Peptides Attack Cell Membranes in a Lipid-Regulated Curvature-Generating Mode.
J Phys Chem Lett
; 14(28): 6422-6430, 2023 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37432779
17.
Targeted therapy for intractable cancer on the basis of molecular profiles: An open-label, phase II basket trial (Long March Pathway).
Front Oncol
; 13: 860711, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36910668
18.
Atomistic Insights into A315E Mutation-Enhanced Pathogenicity of TDP-43 Core Fibrils.
ACS Chem Neurosci
; 13(18): 2743-2754, 2022 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36053560
19.
Green tea extract EGCG plays a dual role in Aß42 protofibril disruption and membrane protection: A molecular dynamic study.
Chem Phys Lipids
; 234: 105024, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33278382
20.
Molecular dynamics simulations reveal the destabilization mechanism of Alzheimer's disease-related tau R3-R4 Protofilament by norepinephrine.
Biophys Chem
; 271: 106541, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515860