Determination of components in Radix paeoniae rubra based on QAMS.

The current study aimed to establish simple and quick quality evaluation method of Chishao based on QAMS. Oxypaeoniflorin is used as a marker in the Chishao root. Based on it, the content of other components could be obtained by establishing the mathematical relationship. UPLC method was used to collect data, and the detection wavelengths were 230nm (benzoic acid, paeoniflorin), 263nm (hydroxy paeoniflorin) 274nm (gallic acid, paeoniflorin, catechin), respectively. The stationary phase was an Agilent ZORBAX SB-C18 and the mobile phase was acetonitrile -0.1% formic acid-water. The gradient elution method was adopted at the certain flow rate (0.3 mL/min). The column temperature set 40oC, and the injection volume was 1µL. Multiple reaction monitoring mode was selected for data collection. The linear ranges of benzoic acid, paeoniflorin, hydroxy-paeoniflorin, gallic acid, catechin and paeoniflorinhad good linearity (r ≥0.9995). The UPLC method was established to determine the content of paeoniflorin, benzoic acid, catechin, gallic acid, paeoniflorin, andhydroxy-paeoniflorin in Radix Paeoniae Rubra. In the current study, the method for the chemical components in Radix Paeoniae Rubra to provide the evaluation basis of medicinal effects.

A novel method for creating a 2-d parameterized finite element model of the human femur with matching artificial hip joint based on x-ray image.

There is a novel method for creating a 2-d parameterized finite element model of the human femur with matching artificial hip joint based on X-ray image before the hip joint replacement surgery. It can help us to evaluate the selected appropriate hip joint prosthesis.

Primary analysis of the first ray using a 3-dimension finite element foot model.

A three-dimensional accurate foot model including bones, cartilages, ligaments and tendons was developed from 3D reconstruction of CT images. The model was used to analyze stress-strain of the joint between the first metatarsal and the medial cuneiform and to study the relationship of the range of motion of the first ray and hallux valgus.