Detalhe da pesquisa
1.
Computational design of transmembrane pores.
Nature
; 585(7823): 129-134, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32848250
2.
De novo design of a fluorescence-activating ß-barrel.
Nature
; 561(7724): 485-491, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209393
3.
Parthenolide, bioactive compound of Chrysanthemum parthenium L., ameliorates fibrogenesis and inflammation in hepatic fibrosis via regulating the crosstalk of TLR4 and STAT3 signaling pathway.
Phytother Res
; 35(10): 5680-5693, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34250656
4.
Computational design of ligand-binding proteins with high affinity and selectivity.
Nature
; 501(7466): 212-216, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24005320
5.
CSAR Benchmark Exercise 2013: Evaluation of Results from a Combined Computational Protein Design, Docking, and Scoring/Ranking Challenge.
J Chem Inf Model
; 56(6): 1022-31, 2016 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26419257
6.
Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage.
Phytomedicine
; 123: 155145, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37976698
7.
Angelica dahurica extract and its effective component bergapten alleviated hepatic fibrosis by activating FXR signaling pathway.
J Nat Med
; 78(2): 427-438, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38334900
8.
Pterostilbene exerts cytotoxicity on activated hepatic stellate cells by inhibiting excessive proliferation through the crosstalk of Sirt1 and STAT3 pathways.
Food Chem Toxicol
; 181: 114042, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722617
9.
Genetically targeted chemical assembly of polymers specifically localized extracellularly to surface membranes of living neurons.
Sci Adv
; 9(32): eadi1870, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37556541
10.
Acanthoic acid, unique potential pimaradiene diterpene isolated from Acanthopanax koreanum Nakai (Araliaceae): A review on its pharmacology, molecular mechanism, and structural modification.
Phytochemistry
; 200: 113247, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35597316
11.
Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation.
Biomol Ther (Seoul)
; 30(3): 246-256, 2022 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815367
12.
Protective role of Siberian onions against toxin-induced liver dysfunction: an insight into health-promoting effects.
Food Funct
; 13(8): 4678-4690, 2022 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377371
13.
[Cuffless blood pressure acquisition system based on a novel calibration method].
Zhongguo Yi Liao Qi Xie Za Zhi
; 35(1): 6-10, 2011 Jan.
Artigo
em Zh
| MEDLINE | ID: mdl-21553528
14.
Allium victorialis L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation.
Front Pharmacol
; 12: 738689, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34690775
15.
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins.
Nat Commun
; 12(1): 856, 2021 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33558528
16.
Parallelized identification of on- and off-target protein interactions.
Mol Syst Des Eng
; 5(1): 349-357, 2020 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35265342
17.
20S-Protopanaxatriol Ameliorates Hepatic Fibrosis, Potentially Involving FXR-Mediated Inflammatory Signaling Cascades.
J Agric Food Chem
; 68(31): 8195-8204, 2020 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32662640
18.
Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations.
J Chem Theory Comput
; 15(10): 5703-5715, 2019 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31442033
19.
Sampling and energy evaluation challenges in ligand binding protein design.
Protein Sci
; 26(12): 2426-2437, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28980354
20.
Principles for designing proteins with cavities formed by curved ß sheets.
Science
; 355(6321): 201-206, 2017 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28082595