Detalhe da pesquisa
1.
Identification of the calpain-generated toxic fragment of ataxin-3 protein provides new avenues for therapy of Machado-Joseph disease| Spinocerebellar ataxia type 3.
Neuropathol Appl Neurobiol
; 48(1): e12748, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34273111
2.
Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis.
Adv Exp Med Biol
; 1049: 349-367, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29427113
3.
Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
Hum Mol Genet
; 24(19): 5451-63, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26220979
4.
Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases.
Neurobiol Dis
; 95: 210-24, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27461050
5.
Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease.
Sci Rep
; 11(1): 3345, 2021 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33558582
6.
Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
Nat Commun
; 7: 11445, 2016 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27165717