Detalhe da pesquisa
1.
Discovery of potent and selective DP1 receptor antagonists in the azaindole series.
Bioorg Med Chem Lett
; 19(8): 2125-8, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19307115
2.
Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold.
Bioorg Med Chem Lett
; 18(8): 2696-700, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18359630
3.
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor.
Bioorg Med Chem Lett
; 18(11): 3200-5, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18477508
4.
Automated agar plate streaker: a linear plater on Society for Biomolecular Sciences standard plates.
J Biomol Screen
; 11(6): 704-11, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16844965
5.
A cell-sparing electric field stimulation technique for high-throughput screening of voltage-gated ion channels.
Assay Drug Dev Technol
; 4(1): 21-35, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16506886
6.
High throughput metabolic stability screen for lead optimization in drug discovery.
J Chromatogr B Analyt Technol Biomed Life Sci
; 833(2): 165-73, 2006 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16504609
7.
FIZICS: fluorescent imaging zone identification system, a novel macro imaging system.
J Biomol Screen
; 9(8): 663-70, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15637029
8.
Label-free high-throughput screening via mass spectrometry: a single cystathionine quantitative method for multiple applications.
Assay Drug Dev Technol
; 7(5): 495-506, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19715455
9.
Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase.
J Biol Chem
; 281(12): 8010-5, 2006 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-16407290
10.
The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.
Biochemistry
; 41(29): 9043-51, 2002 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119018
11.
The development of potent non-peptidic PTP-1B inhibitors.
Bioorg Med Chem Lett
; 14(4): 1039-42, 2004 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15013019