Detalhe da pesquisa
1.
WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
Nature
; 568(7753): 551-556, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30971823
2.
Nanoliposome targeting in breast cancer is influenced by the tumor microenvironment.
Nanomedicine
; 17: 71-81, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30654182
3.
Rare somatic cells from human breast tissue exhibit extensive lineage plasticity.
Proc Natl Acad Sci U S A
; 110(12): 4598-603, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23487770
4.
Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform.
bioRxiv
; 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38826457
5.
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas.
Cancer Discov
; 13(3): 766-795, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36576405
6.
No paradox, no progress: inverse cancer comorbidity in people with other complex diseases.
Lancet Oncol
; 12(6): 604-8, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21498115
7.
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.
Nat Cancer
; 3(6): 681-695, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35437317
8.
Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers.
Proc Natl Acad Sci U S A
; 105(39): 14867-72, 2008 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18806226
9.
Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.
Cancer Discov
; 11(9): 2282-2299, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33883167
10.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Cell Rep
; 33(11): 108493, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326793
11.
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.
Nat Cancer
; 1(2): 235-248, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32613204
12.
Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy.
Breast Cancer Res
; 11(6): R87, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19995452
13.
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models.
Nat Biomed Eng
; 3(4): 264-280, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30952988
14.
Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
Cell Rep
; 29(1): 118-134.e8, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31577942
15.
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.
J Clin Invest
; 109(12): 1551-9, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12070302
16.
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
Mol Cell Biol
; 22(23): 8184-98, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12417722
17.
Targeting the TGF beta signaling network in human neoplasia.
Cancer Cell
; 3(6): 531-6, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12842082
18.
Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression.
Clin Cancer Res
; 11(2 Pt 2): 937s-43s, 2005 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15701890
19.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Cell Rep
; 36(2): 109367, 2021 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260938
20.
Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302).
Mol Cancer Ther
; 14(9): 2060-71, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26162690