Detalhe da pesquisa
1.
N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model.
Bioorg Med Chem
; 26(18): 5169-5180, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30253886
2.
Optimization of Novel Antagonists to the Neurokinin-3 Receptor for the Treatment of Sex-Hormone Disorders (Part II).
ACS Med Chem Lett
; 6(7): 736-40, 2015 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26191358
3.
Discovery and optimization of novel antagonists to the human neurokinin-3 receptor for the treatment of sex-hormone disorders (Part I).
J Med Chem
; 58(7): 3060-82, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25738882
4.
A facile and mild method for the synthesis of terminal bromofluoroolefins via diethylzinc-promoted Wittig reaction.
Org Lett
; 6(13): 2101-4, 2004 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15200295
5.
Stereocontrolled synthesis of carbon chains bearing contiguous methyl groups by iterative boronic ester homologations: application to the total synthesis of (+)-faranal.
Angew Chem Int Ed Engl
; 48(34): 6317-9, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19437526
6.
Diastereomeric fluoroolefins as peptide bond mimics prepared by asymmetric reductive amination of alpha-fluoroenones.
Angew Chem Int Ed Engl
; 46(8): 1290-2, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17205591
7.
Lithiated carbamates: chiral carbenoids for iterative homologation of boranes and boronic esters.
Angew Chem Int Ed Engl
; 46(39): 7491-4, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17659521
8.
New synthesis of cis 5-tert-butyl-L-proline via cuprate. Evaluation as a cis proline mimetic in a biological active octapeptide.
J Pept Sci
; 12(2): 154-60, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16138385
9.
First stereospecific synthesis of (E)- or (Z)-alpha-fluoroenones via a kinetically controlled Negishi coupling reaction.
J Org Chem
; 71(11): 4316-9, 2006 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16709079
10.
A novel diastereoselective synthesis of (Z)-fluoroalkenes via a Nozaki-Hiyama-Kishi-type reaction.
J Org Chem
; 70(5): 1911-4, 2005 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15730321