Detalhe da pesquisa
1.
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
Cell
; 183(3): 739-751.e8, 2020 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32991842
2.
Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Mol Cell
; 82(10): 1836-1849.e5, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35338845
3.
Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.
J Biol Chem
; 299(7): 104880, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37269949
4.
An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
J Biol Chem
; 297(1): 100861, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34116056
5.
Characterization of aminoacyl-tRNA synthetase stability and substrate interaction by differential scanning fluorimetry.
Methods
; 113: 64-71, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27794454
6.
Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination.
Nat Commun
; 14(1): 2527, 2023 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37137903
7.
Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing.
Structure
; 31(9): 1065-1076.e5, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37453417
8.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
Cell Genom
; 3(3): 100250, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36950384
9.
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States.
Cancer Res
; 83(2): 264-284, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409824
10.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.
iScience
; 26(5): 106701, 2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37207277
11.
Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Cell Rep
; 42(12): 113564, 2023 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38100350
12.
Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds.
Sci Data
; 8(1): 226, 2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433823
13.
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
bioRxiv
; 2020 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637944
14.
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Cancer Cell
; 34(6): 939-953.e9, 2018 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30472020
15.
Optimum Exchange for Calculation of Excitation Energies and Hyperpolarizabilities of Organic Electro-optic Chromophores.
J Chem Theory Comput
; 10(9): 3821-31, 2014 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26588527
16.
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Cancer Cell
; 35(2): 330-332, 2019 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753830
17.
A phosphoproteomic signature in endothelial cells predicts vascular toxicity of tyrosine kinase inhibitors used in CML.
Blood Adv
; 2(14): 1680-1684, 2018 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30021779