Detalhe da pesquisa
1.
IKKß inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.
Diabetologia
; 60(10): 2021-2032, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28725915
2.
Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
J Biol Chem
; 291(17): 8908-17, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26786104
3.
Activity of SHIP, Which Prevents Expression of Interleukin 1ß, Is Reduced in Patients With Crohn's Disease.
Gastroenterology
; 150(2): 465-76, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26481854
4.
Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity.
J Immunol
; 192(2): 623-9, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24323581
5.
Targeting 12-lipoxygenase as a novel strategy to combat the effects of inflammation on beta cells in diabetes.
Diabetologia
; 58(3): 425-8, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25537834
6.
IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
Diabetologia
; 58(3): 575-85, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25491100
7.
Is there a role for the adaptive immune system in pancreatic beta cell failure in type 2 diabetes?
Diabetologia
; 57(3): 447-50, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362729
8.
TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6.
Diabetologia
; 57(8): 1645-54, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24816367
9.
Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes.
Immunol Cell Biol
; 92(4): 314-23, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24492799
10.
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.
J Immunol
; 187(5): 2755-65, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21813778
11.
Early reduction of circulating homocysteine levels in Goto-Kakizaki rat, a spontaneous nonobese model of type 2 diabetes.
Biochim Biophys Acta
; 1812(6): 699-702, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21447386
12.
Interleukin-6 regulates pancreatic alpha-cell mass expansion.
Proc Natl Acad Sci U S A
; 105(35): 13163-8, 2008 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18719127
13.
Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.
Physiology (Bethesda)
; 24: 325-31, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19996363
14.
Interleukin-1-receptor antagonist in type 2 diabetes mellitus.
N Engl J Med
; 356(15): 1517-26, 2007 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17429083
15.
Islet Macrophages Shift to a Reparative State following Pancreatic Beta-Cell Death and Are a Major Source of Islet Insulin-like Growth Factor-1.
iScience
; 23(1): 100775, 2020 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31962237
16.
Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.
J Clin Endocrinol Metab
; 93(10): 4065-74, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18664535
17.
Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control.
Cell Metab
; 27(6): 1201-1211.e3, 2018 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29731416
18.
Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.
Endocrinology
; 148(11): 5582-90, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17702850
19.
Mechanisms of beta-cell death in type 2 diabetes.
Diabetes
; 54 Suppl 2: S108-13, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16306327
20.
Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.
Diabetes
; 52(3): 741-50, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12606516