Detalhe da pesquisa
1.
Metformin: review of epidemiology and mechanisms of action in pancreatic cancer.
Cancer Metastasis Rev
; 40(3): 865-878, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34142285
2.
KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.
Semin Cancer Biol
; 54: 50-62, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079305
3.
Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity.
Am J Physiol Gastrointest Liver Physiol
; 317(6): G763-G772, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31545922
4.
Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice.
BMC Cancer
; 18(1): 797, 2018 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30086728
5.
An Appraisal of Current Guidelines for Managing Malignancy in Pancreatic Intraductal Papillary Mucinous Neoplasm.
JOP
; 19(4): 178-182, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30636939
6.
Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.
Am J Physiol Gastrointest Liver Physiol
; 310(11): G1124-37, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27151939
7.
Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells.
Am J Physiol Gastrointest Liver Physiol
; 311(4): G675-G687, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27609771
8.
Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.
Am J Physiol Cell Physiol
; 309(10): C639-49, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26310818
9.
Role of pancreatic cancer-derived exosomes in salivary biomarker development.
J Biol Chem
; 288(37): 26888-97, 2013 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23880764
10.
Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cells.
Biochim Biophys Acta
; 1833(12): 2980-2987, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954445
11.
Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma.
Cancers (Basel)
; 16(8)2024 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672675
12.
Evidence for activation of mutated p53 by apigenin in human pancreatic cancer.
Biochim Biophys Acta
; 1823(2): 593-604, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22227579
13.
The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation.
Gastroenterology
; 142(2): 377-87.e1-5, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22044669
14.
miR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells.
Biochem Biophys Res Commun
; 439(1): 6-11, 2013 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23973710
15.
Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells.
Nutr Cancer
; 65(8): 1232-44, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24127740
16.
Strategies to Prevent Obesity-Related Cancer.
JAMA
; 319(23): 2442, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29922821
17.
Low dosage combination treatment with metformin and simvastatin inhibits obesity-promoted pancreatic cancer development in male KrasG12D mice.
Sci Rep
; 13(1): 16144, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37752238
18.
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells.
Biochim Biophys Acta
; 1813(8): 1465-74, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21596068
19.
Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.
Am J Pathol
; 178(3): 1340-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21356384
20.
Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell.
J Gastroenterol Hepatol
; 27 Suppl 2: 127-34, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22320930