Detalhe da pesquisa
1.
New quinazolinone-based derivatives as DHFR/EGFR-TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity.
Arch Pharm (Weinheim)
; 356(1): e2200417, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36257809
2.
Imidazo[2',1':2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study.
Bioorg Chem
; 80: 11-23, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29864684
3.
Thiazolo[4,5-d]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study.
Bioorg Chem
; 74: 228-237, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28865294
4.
Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3H)-one as DHFR inhibitors.
Bioorg Chem
; 72: 282-292, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28499189