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Enferm Infecc Microbiol Clin (Engl Ed) ; 40(10): 557-561, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-36274043

RESUMO

INTRODUCTION: Congenital citomegalovirus (CMVc) infection is more common in children exposed to HIV during pregnancy, with reported rates in pre-ART era from 2 to 7%. The use of combined antiretroviral treatment (ARTc) could be a determining factor in reducing this risk of CMV transmission. The aim of this study was to describe the epidemiology of CMVc infection in newborns of HIV-infected mothers at Hospital Universitario 12 de Octubre, Madrid, Spain, from 2000 to 2017. MATERIAL AND METHODS: An observational and retrospective study was carried out. Epidemiological and clinical variables were collected. Statistical analysis was performed with the SPSS 24.0 computer program. RESULTS: 288 mother-infant pairs were included in the study. We observed a CMVc rate of 2.1% (95% CI 0.9-4.9). CONCLUSIONS: The rate of CMVc in HIV-exposed children observed was lower than that reported in pre-ARTc era but seems higher than those described in general population.


Assuntos
Infecções por Citomegalovirus , Doenças Fetais , Infecções por HIV , Doenças do Recém-Nascido , Complicações Infecciosas na Gravidez , Lactente , Gravidez , Criança , Feminino , Recém-Nascido , Humanos , Transmissão Vertical de Doenças Infecciosas , Mães , Complicações Infecciosas na Gravidez/epidemiologia , Complicações Infecciosas na Gravidez/tratamento farmacológico , Estudos Retrospectivos , Infecções por HIV/complicações , Infecções por HIV/epidemiologia , Infecções por HIV/tratamento farmacológico , Infecções por Citomegalovirus/epidemiologia , Antirretrovirais/uso terapêutico
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