Detalhe da pesquisa
1.
TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice.
Cell Mol Life Sci
; 80(5): 133, 2023 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37185787
2.
Evaluation of the Antiseizure Activity of Endemic Plant Halfordia kendack Guillaumin and Its Main Constituent, Halfordin, on a Zebrafish Pentylenetetrazole (PTZ)-Induced Seizure Model.
Int J Mol Sci
; 24(3)2023 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768918
3.
SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility.
Acta Neuropathol
; 144(1): 107-127, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35551471
4.
6-Gingerol, a Major Constituent of Zingiber officinale Rhizoma, Exerts Anticonvulsant Activity in the Pentylenetetrazole-Induced Seizure Model in Larval Zebrafish.
Int J Mol Sci
; 22(14)2021 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299361
5.
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome.
Epilepsia
; 61(3): 549-560, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096222
6.
Anticonvulsant Activity of Pterostilbene in Zebrafish and Mouse Acute Seizure Tests.
Neurochem Res
; 44(5): 1043-1055, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30689162
7.
Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B.
Mar Drugs
; 17(11)2019 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31731399
8.
De novo loss-of-function mutations in CHD2 cause a fever-sensitive myoclonic epileptic encephalopathy sharing features with Dravet syndrome.
Am J Hum Genet
; 93(5): 967-75, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24207121
9.
CHD2 variants are a risk factor for photosensitivity in epilepsy.
Brain
; 138(Pt 5): 1198-207, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25783594
10.
Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.
Epilepsy Behav
; 45: 53-63, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25845493
11.
Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?
J Appl Toxicol
; 35(9): 1017-29, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25663337
12.
Smoc2 modulates embryonic myelopoiesis during zebrafish development.
Dev Dyn
; 243(11): 1375-90, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25044883
13.
The plant decapeptide OSIP108 prevents copper-induced toxicity in various models for Wilson disease.
Toxicol Appl Pharmacol
; 280(2): 345-51, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25134866
14.
Inhibition of Seizure-Like Paroxysms and Toxicity Effects of Securidaca longepedunculata Extracts and Constituents in Zebrafish Danio rerio.
ACS Chem Neurosci
; 15(3): 617-628, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38270158
15.
A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies.
Biomed Pharmacother
; 172: 116234, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38325264
16.
Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.
J Nat Prod
; 76(6): 1064-70, 2013 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23806111
17.
Natural product-derived therapies for treating drug-resistant epilepsies: From ethnopharmacology to evidence-based medicine.
J Ethnopharmacol
; 317: 116740, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315641
18.
Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models.
Epilepsy Behav
; 24(1): 14-22, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22483646
19.
Zebrafish bioassay-guided microfractionation for the rapid in vivo identification of pharmacologically active natural products.
Chimia (Aarau)
; 66(4): 229-32, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22613156
20.
From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin.
Pharmaceuticals (Basel)
; 15(2)2022 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35215359