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1.
Front Bioeng Biotechnol ; 11: 1057866, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37020509

RESUMO

Robust skin lesion segmentation of dermoscopic images is still very difficult. Recent methods often take the combinations of CNN and Transformer for feature abstraction and multi-scale features for further classification. Both types of combination in general rely on some forms of feature fusion. This paper considers these fusions from two novel points of view. For abstraction, Transformer is viewed as the affinity exploration of different patch tokens and can be applied to attend CNN features in multiple scales. Consequently, a new fusion module, the Attention-based Transformer-And-CNN fusion module (ATAC), is proposed. ATAC augments the CNN features with more global contexts. For further classification, adaptively combining the information from multiple scales according to their contributions to object recognition is expected. Accordingly, a new fusion module, the GAting-based Multi-Scale fusion module (GAMS), is also introduced, which adaptively weights the information from multiple scales by the light-weighted gating mechanism. Combining ATAC and GAMS leads to a new encoder-decoder-based framework. In this method, ATAC acts as an encoder block to progressively abstract strong CNN features with rich global contexts attended by long-range relations, while GAMS works as an enhancement of the decoder to generate the discriminative features through adaptive fusion of multi-scale ones. This framework is especially good at lesions of varying sizes and shapes and of low contrasts and its performances are demonstrated with extensive experiments on public skin lesion segmentation datasets.

2.
Heliyon ; 9(2): e13081, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36718155

RESUMO

The pancreatic islet is a highly structured micro-organ that produces insulin in response to rising blood glucose. Here we develop a label-free and automatic imaging approach to visualize the islets in situ in diabetic rodents by the synchrotron radiation X-ray phase-contrast microtomography (SRµCT) at the ID17 station of the European Synchrotron Radiation Facility. The large-size images (3.2 mm × 15.97 mm) were acquired in the pancreas in STZ-treated mice and diabetic GK rats. Each pancreas was dissected by 3000 reconstructed images. The image datasets were further analysed by a self-developed deep learning method, AA-Net. All islets in the pancreas were segmented and visualized by the three-dimension (3D) reconstruction. After quantifying the volumes of the islets, we found that the number of larger islets (=>1500 µm3) was reduced by 2-fold (wt 1004 ± 94 vs GK 419 ± 122, P < 0.001) in chronically developed diabetic GK rat, while in STZ-treated diabetic mouse the large islets were decreased by half (189 ± 33 vs 90 ± 29, P < 0.001) compared to the untreated mice. Our study provides a label-free tool for detecting and quantifying pancreatic islets in situ. It implies the possibility of monitoring the state of pancreatic islets in vivo diabetes without labelling.

3.
IEEE Trans Cybern ; 50(3): 997-1008, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30403647

RESUMO

Previous methods on text image motion deblurring seldom consider the sparse characteristics of the blur kernel. This paper proposes a new text image motion deblurring method by exploiting the sparse properties of both text image itself and kernel. It incorporates the L 0 -norm for regularizing the blur kernel in the deblurring model, besides the L 0 sparse priors for the text image and its gradient. Such a L 0 -norm-based model is efficiently optimized by half-quadratic splitting coupled with the fast conjugate descent method. To further improve the quality of the recovered kernel, a structure-preserving kernel denoising method is also developed to filter out the noisy pixels, yielding a clean kernel curve. Experimental results show the superiority of the proposed method. The source code and results are available at: https://github.com/shenjianbing/text-image-deblur.

4.
IEEE Trans Cybern ; 47(12): 4451-4462, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27705877

RESUMO

Existing distance measurement methods either require multiple images and special photographing poses or only measure the height with a special view configuration. We propose a novel image-based method that can measure various types of distance from single image captured by a smart mobile device. The embedded accelerometer is used to determine the view orientation of the device. Consequently, pixels can be back-projected to the ground, thanks to the efficient calibration method using two known distances. Then the distance in pixel is transformed to a real distance in centimeter with a linear model parameterized by the magnification ratio. Various types of distance specified in the image can be computed accordingly. Experimental results demonstrate the effectiveness of the proposed method.

5.
Biosystems ; 108(1-3): 52-62, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22306575

RESUMO

Spiking neural P systems (SN P systems, for short) are a class of distributed parallel computing devices inspired from the way neurons communicate by means of spikes, where neurons work in parallel in the sense that each neuron that can fire should fire, but the work in each neuron is sequential in the sense that at most one rule can be applied at each computation step. In this work, we consider SN P systems with the restriction that at most one neuron can fire at each step, and each neuron works in an exhaustive manner (a kind of local parallelism - an applicable rule in a neuron is used as many times as possible). Such SN P systems are called sequential SN P systems with exhaustive use of rules. The computation power of sequential SN P systems with exhaustive use of rules is investigated. Specifically, characterizations of Turing computability and of semilinear sets of numbers are obtained, as well as a strict superclass of semilinear sets is generated. The results show that the computation power of sequential SN P systems with exhaustive use of rules is closely related with the types of spiking rules in neurons.


Assuntos
Redes Neurais de Computação , Potenciais de Ação/fisiologia , Simulação por Computador , Modelos Neurológicos , Neurônios/fisiologia , Biologia de Sistemas
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