Detalhe da pesquisa
1.
Widespread transcriptional pausing and elongation control at enhancers.
Genes Dev
; 32(1): 26-41, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378787
2.
Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation.
Cell
; 143(4): 540-51, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21074046
3.
SIRT1 regulates cardiomyocyte alignment during maturation.
J Cell Sci
; 135(7)2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35260907
4.
UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin.
PLoS Genet
; 17(1): e1009302, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33444353
5.
INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma.
Genes Dev
; 30(12): 1440-53, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27340176
6.
Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin.
Mol Cell
; 58(6): 1101-12, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26028540
7.
Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks.
Mol Cell
; 58(2): 311-322, 2015 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25773599
8.
Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study.
Environ Res
; 212(Pt D): 113463, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35605674
9.
SIRT1-mediated deacetylation of CRABPII regulates cellular retinoic acid signaling and modulates embryonic stem cell differentiation.
Mol Cell
; 55(6): 843-855, 2014 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25155613
10.
Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.
EMBO J
; 36(21): 3175-3193, 2017 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29021282
11.
ORSO (Online Resource for Social Omics): A data-driven social network connecting scientists to genomics datasets.
PLoS Comput Biol
; 16(1): e1007571, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978042
12.
Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals.
Mol Cell
; 52(4): 517-28, 2013 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24184211
13.
Revealing a human p53 universe.
Nucleic Acids Res
; 46(16): 8153-8167, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30107566
14.
Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks.
Genes Dev
; 26(9): 933-44, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22549956
15.
The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.
EMBO Rep
; 18(5): 841-857, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28364022
16.
ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data.
Nucleic Acids Res
; 45(10): 5678-5690, 2017 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28402545
17.
Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters.
PLoS Genet
; 12(8): e1006224, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27487356
18.
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.
PLoS Genet
; 12(10): e1006385, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27788131
19.
Muver, a computational framework for accurately calling accumulated mutations.
BMC Genomics
; 19(1): 345, 2018 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29743009
20.
Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.
Gastroenterology
; 153(3): 772-786, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28552621