Detalhe da pesquisa
1.
Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background.
Am J Hum Genet
; 110(10): 1817-1824, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37659414
2.
Efficacy and safety of remibrutinib, a selective potent oral BTK inhibitor, in Sjögren's syndrome: results from a randomised, double-blind, placebo-controlled phase 2 trial.
Ann Rheum Dis
; 83(3): 360-371, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37932009
3.
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis.
J Neuroinflammation
; 20(1): 194, 2023 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37633912
4.
Translational precision medicine: an industry perspective.
J Transl Med
; 19(1): 245, 2021 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34090480
5.
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.
Mol Cell
; 42(1): 84-95, 2011 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21474070
6.
STOPGAP: a database for systematic target opportunity assessment by genetic association predictions.
Bioinformatics
; 33(17): 2784-2786, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472345
7.
In silico prediction of novel therapeutic targets using gene-disease association data.
J Transl Med
; 15(1): 182, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28851378
8.
Ten simple rules to power drug discovery with data science.
PLoS Comput Biol
; 16(8): e1008126, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853229
9.
The role of Dichaete in transcriptional regulation during Drosophila embryonic development.
BMC Genomics
; 14: 861, 2013 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24314314
10.
Analysis of serum proteomics data identifies a quantitative association between beta-defensin 2 at baseline and clinical response to IL-17 blockade in psoriatic arthritis.
RMD Open
; 9(2)2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37321668
11.
Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy.
Cell Rep Med
; 4(5): 101036, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196635
12.
Brown meagre vocalization rate increases during repetitive boat noise exposures: a possible case of vocal compensation.
J Acoust Soc Am
; 132(5): 3118-24, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23145597
13.
Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints.
Front Immunol
; 12: 651475, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33968050
14.
CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo.
Oncogenesis
; 10(4): 32, 2021 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33824280
15.
Latent Factor Modeling of scRNA-Seq Data Uncovers Dysregulated Pathways in Autoimmune Disease Patients.
iScience
; 23(9): 101451, 2020 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853994
16.
Whole-Genome DNA Methylation Profiling of CD14+ Monocytes Reveals Disease Status and Activity Differences in Crohn's Disease Patients.
J Clin Med
; 9(4)2020 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32276386
17.
Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo.
Front Immunol
; 10: 2887, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31921150
18.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
Nat Commun
; 10(1): 4513, 2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586073
19.
Functional aspects of cHH C-terminal amidation in crayfish species.
Regul Pept
; 147(1-3): 88-95, 2008 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18281112
20.
Using regulatory genomics data to interpret the function of disease variants and prioritise genes from expression studies.
F1000Res
; 7: 121, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29568492