Detalhe da pesquisa
1.
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
J Pharmacol Exp Ther
; 343(1): 233-45, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815533
2.
Structure-activity studies of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.
J Med Chem
; 50(24): 6265-73, 2007 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17973362
3.
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
J Med Chem
; 50(1): 149-64, 2007 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17201418
4.
Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.
J Med Chem
; 49(15): 4459-69, 2006 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16854051
5.
2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.
J Med Chem
; 49(8): 2568-78, 2006 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16610800
6.
Cardiovascular disease in chronic kidney failure: the role of VDR activators.
Curr Opin Investig Drugs
; 7(3): 206-13, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16555680
7.
Differential effects of Vitamin D analogs on bone formation and resorption.
J Steroid Biochem Mol Biol
; 98(1): 72-7, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16242929
8.
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.
Eur J Pharmacol
; 532(1-2): 107-14, 2006 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16487510
9.
Synthesis and structure-activity relationships of a novel series of 2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide K(ATP) channel openers: discovery of (-)-(9S)-9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637), a potent K(ATP) opener that selectively inhibits spontaneous bladder contractions.
J Med Chem
; 47(12): 3163-79, 2004 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15163196
10.
Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.
J Cardiovasc Pharmacol
; 49(4): 228-35, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17438408
11.
Effects of ATP-sensitive K+ channel openers and tolterodine on involuntary bladder contractions in a pig model of partial bladder outlet obstruction.
Neurourol Urodyn
; 22(2): 147-55, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12579633
12.
(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. II. in vivo characterization.
J Pharmacol Exp Ther
; 303(1): 387-94, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12235275