Detalhe da pesquisa
1.
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.
PLoS Biol
; 21(8): e3002217, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37535677
2.
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Proc Natl Acad Sci U S A
; 119(5)2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35074873
3.
Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor.
Mol Pharm
; 20(7): 3367-3379, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37260417
4.
Brevetoxin versus Brevenal Modulation of Human Nav1 Channels.
Mar Drugs
; 21(7)2023 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37504927
5.
An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses.
Proc Natl Acad Sci U S A
; 117(10): 5494-5501, 2020 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32079727
6.
Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels.
Proc Natl Acad Sci U S A
; 116(3): 1059-1064, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30593566
7.
A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells.
Exp Cell Res
; 395(2): 112210, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32750330
8.
N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity.
Cancer Cell Int
; 20: 170, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32467666
9.
Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds.
Mar Drugs
; 18(3)2020 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32245015
10.
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET.
Proc Natl Acad Sci U S A
; 114(10): E1857-E1865, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28202723
11.
Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA.
Mar Drugs
; 17(9)2019 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31470595
12.
NMR Structure of µ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency.
Molecules
; 23(10)2018 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30360356
13.
Touch sensation requires the mechanically gated ion channel ELKIN1.
Science
; 383(6686): 992-998, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38422143
14.
Calcium Imaging of Non-adherent Cells.
Methods Mol Biol
; 2644: 361-369, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142934
15.
Nicotinic acetylcholine receptors: Key targets for attenuating neurodegenerative diseases.
Int J Biochem Cell Biol
; 157: 106387, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754161
16.
Evidence of Cytolysin A nanopore incorporation in mammalian cells assessed by a graphical user interface.
Nanoscale
; 15(42): 16914-16923, 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853831
17.
Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability.
Br J Pharmacol
; 179(1): 179-198, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599513
18.
µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site.
Elife
; 112022 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858123
19.
Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine.
Front Mol Neurosci
; 15: 892820, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35928792
20.
Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins.
J Biol Chem
; 285(20): 14882-14889, 2010 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20220134